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Enhanced TLR-mediated NF-IL6 dependent gene expression by Trib1 deficiency.
Yamamoto M, Uematsu S, Okamoto T, Matsuura Y, Sato S, Kumar H, Satoh T, Saitoh T, Takeda K, Ishii KJ, Takeuchi O, Kawai T, Akira S. Yamamoto M, et al. Among authors: akira s. J Exp Med. 2007 Sep 3;204(9):2233-9. doi: 10.1084/jem.20070183. Epub 2007 Aug 27. J Exp Med. 2007. PMID: 17724128 Free PMC article.
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production.
Saitoh T, Fujita N, Jang MH, Uematsu S, Yang BG, Satoh T, Omori H, Noda T, Yamamoto N, Komatsu M, Tanaka K, Kawai T, Tsujimura T, Takeuchi O, Yoshimori T, Akira S. Saitoh T, et al. Among authors: akira s. Nature. 2008 Nov 13;456(7219):264-8. doi: 10.1038/nature07383. Epub 2008 Oct 5. Nature. 2008. PMID: 18849965
Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response.
Saitoh T, Fujita N, Hayashi T, Takahara K, Satoh T, Lee H, Matsunaga K, Kageyama S, Omori H, Noda T, Yamamoto N, Kawai T, Ishii K, Takeuchi O, Yoshimori T, Akira S. Saitoh T, et al. Among authors: akira s. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20842-6. doi: 10.1073/pnas.0911267106. Epub 2009 Nov 19. Proc Natl Acad Sci U S A. 2009. PMID: 19926846 Free PMC article.
LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses.
Satoh T, Kato H, Kumagai Y, Yoneyama M, Sato S, Matsushita K, Tsujimura T, Fujita T, Akira S, Takeuchi O. Satoh T, et al. Among authors: akira s. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1512-7. doi: 10.1073/pnas.0912986107. Epub 2010 Jan 8. Proc Natl Acad Sci U S A. 2010. PMID: 20080593 Free PMC article.
IκBζ is essential for natural killer cell activation in response to IL-12 and IL-18.
Miyake T, Satoh T, Kato H, Matsushita K, Kumagai Y, Vandenbon A, Tani T, Muta T, Akira S, Takeuchi O. Miyake T, et al. Among authors: akira s. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17680-5. doi: 10.1073/pnas.1012977107. Epub 2010 Sep 27. Proc Natl Acad Sci U S A. 2010. PMID: 20876105 Free PMC article.
1,325 results