Lomas DA - Search Results

1

The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z-α1-antitrypsin.

Dickens JA, Ordóñez A, Chambers JE, Beckett AJ, Patel V, Malzer E, Dominicus CS, Bradley J, Peden AA, Prior IA, Lomas DA, Marciniak SJ. Dickens JA, et al. Among authors: lomas da. FASEB J. 2016 Dec;30(12):4083-4097. doi: 10.1096/fj.201600430R. Epub 2016 Sep 6. FASEB J. 2016. PMID: 27601439 Free PMC article.

2

Alpha(1)-antitrypsin deficiency, liver disease and emphysema.

Parfrey H, Mahadeva R, Lomas DA. Parfrey H, et al. Among authors: lomas da. Int J Biochem Cell Biol. 2003 Jul;35(7):1009-14. doi: 10.1016/s1357-2725(02)00250-9. Int J Biochem Cell Biol. 2003. PMID: 12672469 Review.

3

The selective advantage of alpha1-antitrypsin deficiency.

Lomas DA. Lomas DA. Am J Respir Crit Care Med. 2006 May 15;173(10):1072-7. doi: 10.1164/rccm.200511-1797PP. Epub 2006 Jan 26. Am J Respir Crit Care Med. 2006. PMID: 16439713 Review.

4

Intracellular serpins, firewalls and tissue necrosis.

Marciniak SJ, Lomas DA. Marciniak SJ, et al. Among authors: lomas da. Trends Cell Biol. 2008 Feb;18(2):45-7. doi: 10.1016/j.tcb.2007.11.006. Epub 2008 Jan 22. Trends Cell Biol. 2008. PMID: 18215520

5

Neuroserpin polymers activate NF-kappaB by a calcium signaling pathway that is independent of the unfolded protein response.

Davies MJ, Miranda E, Roussel BD, Kaufman RJ, Marciniak SJ, Lomas DA. Davies MJ, et al. Among authors: lomas da. J Biol Chem. 2009 Jul 3;284(27):18202-9. doi: 10.1074/jbc.M109.010744. Epub 2009 May 7. J Biol Chem. 2009. PMID: 19423713 Free PMC article.

6

alpha1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies.

Ekeowa UI, Gooptu B, Belorgey D, Hägglöf P, Karlsson-Li S, Miranda E, Pérez J, MacLeod I, Kroger H, Marciniak SJ, Crowther DC, Lomas DA. Ekeowa UI, et al. Among authors: lomas da. Clin Sci (Lond). 2009 May 14;116(12):837-50. doi: 10.1042/CS20080484. Clin Sci (Lond). 2009. PMID: 19426146 Review.

7

Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins.

Kroeger H, Miranda E, MacLeod I, Pérez J, Crowther DC, Marciniak SJ, Lomas DA. Kroeger H, et al. Among authors: lomas da. J Biol Chem. 2009 Aug 21;284(34):22793-802. doi: 10.1074/jbc.M109.027102. Epub 2009 Jun 23. J Biol Chem. 2009. PMID: 19549782 Free PMC article.

8

A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with alpha1-antitrypsin deficiency.

Miranda E, Pérez J, Ekeowa UI, Hadzic N, Kalsheker N, Gooptu B, Portmann B, Belorgey D, Hill M, Chambers S, Teckman J, Alexander GJ, Marciniak SJ, Lomas DA. Miranda E, et al. Among authors: lomas da. Hepatology. 2010 Sep;52(3):1078-88. doi: 10.1002/hep.23760. Hepatology. 2010. PMID: 20583215

9

Impaired tissue growth is mediated by checkpoint kinase 1 (CHK1) in the integrated stress response.

Malzer E, Daly ML, Moloney A, Sendall TJ, Thomas SE, Ryder E, Ryoo HD, Crowther DC, Lomas DA, Marciniak SJ. Malzer E, et al. Among authors: lomas da. J Cell Sci. 2010 Sep 1;123(Pt 17):2892-900. doi: 10.1242/jcs.070078. Epub 2010 Aug 3. J Cell Sci. 2010. PMID: 20682638 Free PMC article.

10

Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells.

Rashid ST, Corbineau S, Hannan N, Marciniak SJ, Miranda E, Alexander G, Huang-Doran I, Griffin J, Ahrlund-Richter L, Skepper J, Semple R, Weber A, Lomas DA, Vallier L. Rashid ST, et al. Among authors: lomas da. J Clin Invest. 2010 Sep;120(9):3127-36. doi: 10.1172/JCI43122. Epub 2010 Aug 25. J Clin Invest. 2010. PMID: 20739751 Free PMC article.

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