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Targeting the correct HDAC(s) to treat cognitive disorders.
Fischer A, Sananbenesi F, Mungenast A, Tsai LH. Fischer A, et al. Among authors: tsai lh. Trends Pharmacol Sci. 2010 Dec;31(12):605-17. doi: 10.1016/j.tips.2010.09.003. Epub 2010 Oct 25. Trends Pharmacol Sci. 2010. PMID: 20980063 Review.
An epigenetic blockade of cognitive functions in the neurodegenerating brain.
Gräff J, Rei D, Guan JS, Wang WY, Seo J, Hennig KM, Nieland TJ, Fass DM, Kao PF, Kahn M, Su SC, Samiei A, Joseph N, Haggarty SJ, Delalle I, Tsai LH. Gräff J, et al. Among authors: tsai lh. Nature. 2012 Feb 29;483(7388):222-6. doi: 10.1038/nature10849. Nature. 2012. PMID: 22388814 Free PMC article.
Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons.
Chung CY, Khurana V, Auluck PK, Tardiff DF, Mazzulli JR, Soldner F, Baru V, Lou Y, Freyzon Y, Cho S, Mungenast AE, Muffat J, Mitalipova M, Pluth MD, Jui NT, Schüle B, Lippard SJ, Tsai LH, Krainc D, Buchwald SL, Jaenisch R, Lindquist S. Chung CY, et al. Among authors: tsai lh. Science. 2013 Nov 22;342(6161):983-7. doi: 10.1126/science.1245296. Epub 2013 Oct 24. Science. 2013. PMID: 24158904 Free PMC article.
Neuronal differentiation: 5-HT6R can do it alone.
Seo J, Tsai LH. Seo J, et al. Among authors: tsai lh. Nat Chem Biol. 2014 Jul;10(7):488-9. doi: 10.1038/nchembio.1557. Nat Chem Biol. 2014. PMID: 24937065 No abstract available.
423 results