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MAVS-dependent host species range and pathogenicity of human hepatitis A virus.
Hirai-Yuki A, Hensley L, McGivern DR, González-López O, Das A, Feng H, Sun L, Wilson JE, Hu F, Feng Z, Lovell W, Misumi I, Ting JP, Montgomery S, Cullen J, Whitmire JK, Lemon SM. Hirai-Yuki A, et al. Science. 2016 Sep 30;353(6307):1541-1545. doi: 10.1126/science.aaf8325. Epub 2016 Sep 15. Science. 2016. PMID: 27633528 Free PMC article.
Protein composition of the hepatitis A virus quasi-envelope.
McKnight KL, Xie L, González-López O, Rivera-Serrano EE, Chen X, Lemon SM. McKnight KL, et al. Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):6587-6592. doi: 10.1073/pnas.1619519114. Epub 2017 May 10. Proc Natl Acad Sci U S A. 2017. PMID: 28490497 Free PMC article.
Basal expression of interferon regulatory factor 1 drives intrinsic hepatocyte resistance to multiple RNA viruses.
Yamane D, Feng H, Rivera-Serrano EE, Selitsky SR, Hirai-Yuki A, Das A, McKnight KL, Misumi I, Hensley L, Lovell W, González-López O, Suzuki R, Matsuda M, Nakanishi H, Ohto-Nakanishi T, Hishiki T, Wauthier E, Oikawa T, Morita K, Reid LM, Sethupathy P, Kohara M, Whitmire JK, Lemon SM. Yamane D, et al. Nat Microbiol. 2019 Jul;4(7):1096-1104. doi: 10.1038/s41564-019-0425-6. Epub 2019 Apr 15. Nat Microbiol. 2019. PMID: 30988429 Free PMC article.
IRF3-mediated pathogenicity in a murine model of human hepatitis A.
Sun L, Li Y, Misumi I, González-López O, Hensley L, Cullen JM, McGivern DR, Matsuda M, Suzuki R, Sen GC, Hirai-Yuki A, Whitmire JK, Lemon SM. Sun L, et al. PLoS Pathog. 2021 Sep 30;17(9):e1009960. doi: 10.1371/journal.ppat.1009960. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34591933 Free PMC article.
Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIX.
Shirasaki T, Feng H, Duyvesteyn HME, Fusco WG, McKnight KL, Xie L, Boyce M, Kumar S, Barouch-Bentov R, González-López O, McNamara R, Wang L, Hertel-Wulff A, Chen X, Einav S, Duncan JA, Kapustina M, Fry EE, Stuart DI, Lemon SM. Shirasaki T, et al. PLoS Pathog. 2022 Aug 15;18(8):e1010543. doi: 10.1371/journal.ppat.1010543. eCollection 2022 Aug. PLoS Pathog. 2022. PMID: 35969644 Free PMC article.
304 results