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The root causes of pharmacodynamic assay failure.
Ferry-Galow KV, Makhlouf HR, Wilsker DF, Lawrence SM, Pfister TD, Marrero AM, Bigelow KM, Yutzy WH, Ji JJ, Butcher DO, Gouker BA, Kummar S, Chen AP, Kinders RJ, Parchment RE, Doroshow JH. Ferry-Galow KV, et al. Among authors: lawrence sm. Semin Oncol. 2016 Aug;43(4):484-91. doi: 10.1053/j.seminoncol.2016.06.006. Epub 2016 Jun 15. Semin Oncol. 2016. PMID: 27663480 Review.
Development of a validated immunofluorescence assay for γH2AX as a pharmacodynamic marker of topoisomerase I inhibitor activity.
Kinders RJ, Hollingshead M, Lawrence S, Ji J, Tabb B, Bonner WM, Pommier Y, Rubinstein L, Evrard YA, Parchment RE, Tomaszewski J, Doroshow JH; National Cancer Institute Phase 0 Clinical Trials Team. Kinders RJ, et al. Clin Cancer Res. 2010 Nov 15;16(22):5447-57. doi: 10.1158/1078-0432.CCR-09-3076. Epub 2010 Oct 5. Clin Cancer Res. 2010. PMID: 20924131 Free PMC article.
NANOG modulates stemness in human colorectal cancer.
Zhang J, Espinoza LA, Kinders RJ, Lawrence SM, Pfister TD, Zhou M, Veenstra TD, Thorgeirsson SS, Jessup JM. Zhang J, et al. Among authors: lawrence sm. Oncogene. 2013 Sep 12;32(37):4397-405. doi: 10.1038/onc.2012.461. Epub 2012 Oct 22. Oncogene. 2013. PMID: 23085761 Free PMC article.
Cediranib for metastatic alveolar soft part sarcoma.
Kummar S, Allen D, Monks A, Polley EC, Hose CD, Ivy SP, Turkbey IB, Lawrence S, Kinders RJ, Choyke P, Simon R, Steinberg SM, Doroshow JH, Helman L. Kummar S, et al. Among authors: lawrence s. J Clin Oncol. 2013 Jun 20;31(18):2296-302. doi: 10.1200/JCO.2012.47.4288. Epub 2013 Apr 29. J Clin Oncol. 2013. PMID: 23630200 Free PMC article. Clinical Trial.
Characterization of Batracylin-induced Renal and Bladder Toxicity in Rats.
Davis M, Bunin DI, Samuelsson SJ, Altera KP, Kinders RJ, Lawrence SM, Ji J, Ames MM, Buhrow SA, Walden C, Reid JM, Rausch LL, Parman T. Davis M, et al. Among authors: lawrence sm. Toxicol Pathol. 2015 Jun;43(4):519-29. doi: 10.1177/0192623314548766. Epub 2014 Oct 1. Toxicol Pathol. 2015. PMID: 25274659 Free PMC article.
3D Models of the NCI60 Cell Lines for Screening Oncology Compounds.
Selby M, Delosh R, Laudeman J, Ogle C, Reinhart R, Silvers T, Lawrence S, Kinders R, Parchment R, Teicher BA, Evans DM. Selby M, et al. SLAS Discov. 2017 Jun;22(5):473-483. doi: 10.1177/2472555217697434. Epub 2017 Mar 13. SLAS Discov. 2017. PMID: 28288283 Free article.
Antibody-independent capture of circulating tumor cells of non-epithelial origin with the ApoStream® system.
Balasubramanian P, Kinders RJ, Kummar S, Gupta V, Hasegawa D, Menachery A, Lawrence SM, Wang L, Ferry-Galow K, Davis D, Parchment RE, Tomaszewski JE, Doroshow JH. Balasubramanian P, et al. Among authors: lawrence sm. PLoS One. 2017 Apr 12;12(4):e0175414. doi: 10.1371/journal.pone.0175414. eCollection 2017. PLoS One. 2017. PMID: 28403214 Free PMC article.
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