Type I interferon causes thrombotic microangiopathy by a dose-dependent toxic effect on the microvasculature.
Kavanagh D, McGlasson S, Jury A, Williams J, Scolding N, Bellamy C, Gunther C, Ritchie D, Gale DP, Kanwar YS, Challis R, Buist H, Overell J, Weller B, Flossmann O, Blunden M, Meyer EP, Krucker T, Evans SJ, Campbell IL, Jackson AP, Chandran S, Hunt DP.
Kavanagh D, et al. Among authors: krucker t.
Blood. 2016 Dec 15;128(24):2824-2833. doi: 10.1182/blood-2016-05-715987. Epub 2016 Sep 23.
Blood. 2016.
PMID: 27663672
Free PMC article.