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269 results

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Rapamycin Attenuates Cardiac Fibrosis in Experimental Uremic Cardiomyopathy by Reducing Marinobufagenin Levels and Inhibiting Downstream Pro-Fibrotic Signaling.
Haller ST, Yan Y, Drummond CA, Xie J, Tian J, Kennedy DJ, Shilova VY, Xie Z, Liu J, Cooper CJ, Malhotra D, Shapiro JI, Fedorova OV, Bagrov AY. Haller ST, et al. Among authors: shapiro ji. J Am Heart Assoc. 2016 Sep 30;5(10):e004106. doi: 10.1161/JAHA.116.004106. J Am Heart Assoc. 2016. PMID: 27694325 Free PMC article.
Marinobufagenin stimulates fibroblast collagen production and causes fibrosis in experimental uremic cardiomyopathy.
Elkareh J, Kennedy DJ, Yashaswi B, Vetteth S, Shidyak A, Kim EG, Smaili S, Periyasamy SM, Hariri IM, Fedorova L, Liu J, Wu L, Kahaleh MB, Xie Z, Malhotra D, Fedorova OV, Kashkin VA, Bagrov AY, Shapiro JI. Elkareh J, et al. Among authors: shapiro ji. Hypertension. 2007 Jan;49(1):215-24. doi: 10.1161/01.HYP.0000252409.36927.05. Epub 2006 Dec 4. Hypertension. 2007. PMID: 17145984
Partial nephrectomy as a model for uremic cardiomyopathy in the mouse.
Kennedy DJ, Elkareh J, Shidyak A, Shapiro AP, Smaili S, Mutgi K, Gupta S, Tian J, Morgan E, Khouri S, Cooper CJ, Periyasamy SM, Xie Z, Malhotra D, Fedorova OV, Bagrov AY, Shapiro JI. Kennedy DJ, et al. Among authors: shapiro ap, shapiro ji. Am J Physiol Renal Physiol. 2008 Feb;294(2):F450-4. doi: 10.1152/ajprenal.00472.2007. Epub 2007 Nov 21. Am J Physiol Renal Physiol. 2008. PMID: 18032546 Free PMC article.
Marinobufagenin induces increases in procollagen expression in a process involving protein kinase C and Fli-1: implications for uremic cardiomyopathy.
Elkareh J, Periyasamy SM, Shidyak A, Vetteth S, Schroeder J, Raju V, Hariri IM, El-Okdi N, Gupta S, Fedorova L, Liu J, Fedorova OV, Kahaleh MB, Xie Z, Malhotra D, Watson DK, Bagrov AY, Shapiro JI. Elkareh J, et al. Among authors: shapiro ji. Am J Physiol Renal Physiol. 2009 May;296(5):F1219-26. doi: 10.1152/ajprenal.90710.2008. Epub 2009 Mar 4. Am J Physiol Renal Physiol. 2009. PMID: 19261738 Free PMC article.
Spironolactone attenuates experimental uremic cardiomyopathy by antagonizing marinobufagenin.
Tian J, Shidyak A, Periyasamy SM, Haller S, Taleb M, El-Okdi N, Elkareh J, Gupta S, Gohara S, Fedorova OV, Cooper CJ, Xie Z, Malhotra D, Bagrov AY, Shapiro JI. Tian J, et al. Among authors: shapiro ji. Hypertension. 2009 Dec;54(6):1313-20. doi: 10.1161/HYPERTENSIONAHA.109.140038. Epub 2009 Nov 2. Hypertension. 2009. PMID: 19884563 Free PMC article.
Endogenous cardiotonic steroids and salt-sensitive hypertension.
Fedorova OV, Shapiro JI, Bagrov AY. Fedorova OV, et al. Among authors: shapiro ji. Biochim Biophys Acta. 2010 Dec;1802(12):1230-6. doi: 10.1016/j.bbadis.2010.03.011. Epub 2010 Mar 27. Biochim Biophys Acta. 2010. PMID: 20347967 Free PMC article. Review.
269 results