Parker RA - Search Results

1

A potent, tissue-selective, synthetic inhibitor of HMG-CoA reductase.

Balasubramanian N, Brown PJ, Catt JD, Han WT, Parker RA, Sit SY, Wright JJ. Balasubramanian N, et al. Among authors: parker ra. J Med Chem. 1989 Sep;32(9):2038-41. doi: 10.1021/jm00129a004. J Med Chem. 1989. PMID: 2769677 No abstract available.

2

Hypocholesterolemic activity of synthetic and natural tocotrienols.

Pearce BC, Parker RA, Deason ME, Qureshi AA, Wright JJ. Pearce BC, et al. Among authors: parker ra. J Med Chem. 1992 Oct 2;35(20):3595-606. doi: 10.1021/jm00098a002. J Med Chem. 1992. PMID: 1433170

3

Synthesis, biological profile, and quantitative structure-activity relationship of a series of novel 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors.

Sit SY, Parker RA, Motoc I, Han W, Balasubramanian N, Catt JD, Brown PJ, Harte WE, Thompson MD, Wright JJ. Sit SY, et al. Among authors: parker ra. J Med Chem. 1990 Nov;33(11):2982-99. doi: 10.1021/jm00173a013. J Med Chem. 1990. PMID: 2231596

4

Selective inhibition of cholesterol synthesis in liver versus extrahepatic tissues by HMG-CoA reductase inhibitors.

Parker RA, Clark RW, Sit SY, Lanier TL, Grosso RA, Wright JJ. Parker RA, et al. J Lipid Res. 1990 Jul;31(7):1271-82. J Lipid Res. 1990. PMID: 2401858 Free article.

5

Inhibitors of cholesterol biosynthesis. 2. Hypocholesterolemic and antioxidant activities of benzopyran and tetrahydronaphthalene analogues of the tocotrienols.

Pearce BC, Parker RA, Deason ME, Dischino DD, Gillespie E, Qureshi AA, Volk K, Wright JJ. Pearce BC, et al. Among authors: parker ra. J Med Chem. 1994 Feb 18;37(4):526-41. doi: 10.1021/jm00030a012. J Med Chem. 1994. PMID: 8120870

6

Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

Parker RA, Pearce BC, Clark RW, Gordon DA, Wright JJ. Parker RA, et al. J Biol Chem. 1993 May 25;268(15):11230-8. J Biol Chem. 1993. PMID: 8388388 Free article.

7

A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.

NIHR Global Health Research Unit on Global Surgery; STARSurg Collaborative. NIHR Global Health Research Unit on Global Surgery, et al. Lancet Digit Health. 2024 Jul;6(7):e507-e519. doi: 10.1016/S2589-7500(24)00065-7. Lancet Digit Health. 2024. PMID: 38906616 Free article.

8

Phosphorylation and degradation of HMG CoA reductase.

Miller SJ, Parker RA, Gibson DM. Miller SJ, et al. Among authors: parker ra. Adv Enzyme Regul. 1989;28:65-77. doi: 10.1016/0065-2571(89)90064-2. Adv Enzyme Regul. 1989. PMID: 2624176

9

Phosphorylation state of HMG CoA reductase affects its catalytic activity and degradation.

Parker RA, Miller SJ, Gibson DM. Parker RA, et al. Adv Enzyme Regul. 1986;25:329-43. doi: 10.1016/0065-2571(86)90022-1. Adv Enzyme Regul. 1986. PMID: 3028050

10

Regulation of liver hydroxymethylglutaryl-CoA reductase by a bicyclic phosphorylation system.

Ingebritsen TS, Parker RA, Gibson DM. Ingebritsen TS, et al. Among authors: parker ra. J Biol Chem. 1981 Feb 10;256(3):1138-44. J Biol Chem. 1981. PMID: 6256385 Free article. No abstract available.

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