Lokau J - Search Results

1

Circulating Soluble IL-6R but Not ADAM17 Activation Drives Mononuclear Cell Migration in Tissue Inflammation.

Schumacher N, Schmidt S, Schwarz J, Dohr D, Lokau J, Scheller J, Garbers C, Chalaris A, Rose-John S, Rabe B. Schumacher N, et al. Among authors: lokau j. J Immunol. 2016 Nov 1;197(9):3705-3715. doi: 10.4049/jimmunol.1600909. Epub 2016 Oct 3. J Immunol. 2016. PMID: 27698010

2

The membrane-proximal domain of A Disintegrin and Metalloprotease 17 (ADAM17) is responsible for recognition of the interleukin-6 receptor and interleukin-1 receptor II.

Lorenzen I, Lokau J, Düsterhöft S, Trad A, Garbers C, Scheller J, Rose-John S, Grötzinger J. Lorenzen I, et al. Among authors: lokau j. FEBS Lett. 2012 Apr 24;586(8):1093-100. doi: 10.1016/j.febslet.2012.03.012. Epub 2012 Mar 21. FEBS Lett. 2012. PMID: 22575642 Free article.

3

A disintegrin and metalloprotease 17 dynamic interaction sequence, the sweet tooth for the human interleukin 6 receptor.

Düsterhöft S, Höbel K, Oldefest M, Lokau J, Waetzig GH, Chalaris A, Garbers C, Scheller J, Rose-John S, Lorenzen I, Grötzinger J. Düsterhöft S, et al. Among authors: lokau j. J Biol Chem. 2014 Jun 6;289(23):16336-48. doi: 10.1074/jbc.M114.557322. Epub 2014 Apr 30. J Biol Chem. 2014. PMID: 24790088 Free PMC article.

4

The interleukin-6 receptor Asp358Ala single nucleotide polymorphism rs2228145 confers increased proteolytic conversion rates by ADAM proteases.

Garbers C, Monhasery N, Aparicio-Siegmund S, Lokau J, Baran P, Nowell MA, Jones SA, Rose-John S, Scheller J. Garbers C, et al. Among authors: lokau j. Biochim Biophys Acta. 2014 Sep;1842(9):1485-94. doi: 10.1016/j.bbadis.2014.05.018. Epub 2014 May 27. Biochim Biophys Acta. 2014. PMID: 24878322 Free article.

5

Recombinant p35 from bacteria can form Interleukin (IL-)12, but Not IL-35.

Aparicio-Siegmund S, Moll JM, Lokau J, Grusdat M, Schröder J, Plöhn S, Rose-John S, Grötzinger J, Lang PA, Scheller J, Garbers C. Aparicio-Siegmund S, et al. Among authors: lokau j. PLoS One. 2014 Sep 26;9(9):e107990. doi: 10.1371/journal.pone.0107990. eCollection 2014. PLoS One. 2014. PMID: 25259790 Free PMC article.

6

Modular organization of Interleukin-6 and Interleukin-11 α-receptors.

Nitz R, Lokau J, Aparicio-Siegmund S, Scheller J, Garbers C. Nitz R, et al. Among authors: lokau j. Biochimie. 2015 Dec;119:175-82. doi: 10.1016/j.biochi.2015.11.005. Epub 2015 Nov 10. Biochimie. 2015. PMID: 26551279

7

Proteolytic Cleavage Governs Interleukin-11 Trans-signaling.

Lokau J, Nitz R, Agthe M, Monhasery N, Aparicio-Siegmund S, Schumacher N, Wolf J, Möller-Hackbarth K, Waetzig GH, Grötzinger J, Müller-Newen G, Rose-John S, Scheller J, Garbers C. Lokau J, et al. Cell Rep. 2016 Feb 23;14(7):1761-1773. doi: 10.1016/j.celrep.2016.01.053. Epub 2016 Feb 11. Cell Rep. 2016. PMID: 26876177 Free article.

8

Cleavage Site Localization Differentially Controls Interleukin-6 Receptor Proteolysis by ADAM10 and ADAM17.

Riethmueller S, Ehlers JC, Lokau J, Düsterhöft S, Knittler K, Dombrowsky G, Grötzinger J, Rabe B, Rose-John S, Garbers C. Riethmueller S, et al. Among authors: lokau j. Sci Rep. 2016 May 6;6:25550. doi: 10.1038/srep25550. Sci Rep. 2016. PMID: 27151651 Free PMC article.

9

Transcytosis of IL-11 and Apical Redirection of gp130 Is Mediated by IL-11α Receptor.

Monhasery N, Moll J, Cuman C, Franke M, Lamertz L, Nitz R, Görg B, Häussinger D, Lokau J, Floss DM, Piekorz R, Dimitriadis E, Garbers C, Scheller J. Monhasery N, et al. Among authors: lokau j. Cell Rep. 2016 Jul 26;16(4):1067-1081. doi: 10.1016/j.celrep.2016.06.062. Epub 2016 Jul 14. Cell Rep. 2016. PMID: 27425614 Free article.

10

Generation of Soluble Interleukin-11 and Interleukin-6 Receptors: A Crucial Function for Proteases during Inflammation.

Lokau J, Agthe M, Garbers C. Lokau J, et al. Mediators Inflamm. 2016;2016:1785021. doi: 10.1155/2016/1785021. Epub 2016 Jul 14. Mediators Inflamm. 2016. PMID: 27493449 Free PMC article. Review.

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