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SENP1 regulates IFN-γ-STAT1 signaling through STAT3-SOCS3 negative feedback loop.
Yu T, Zuo Y, Cai R, Huang X, Wu S, Zhang C, Chin YE, Li D, Zhang Z, Xia N, Wang Q, Shen H, Yao X, Zhang ZY, Xue S, Shen L, Cheng J. Yu T, et al. Among authors: zhang c, zhang zy, zhang z. J Mol Cell Biol. 2017 Apr 1;9(2):144-153. doi: 10.1093/jmcb/mjw042. J Mol Cell Biol. 2017. PMID: 27702761 Free PMC article.
Negative regulation of Stat3 by activating PTPN11 mutants contributes to the pathogenesis of Noonan syndrome and juvenile myelomonocytic leukemia.
Zhang W, Chan RJ, Chen H, Yang Z, He Y, Zhang X, Luo Y, Yin F, Moh A, Miller LC, Payne RM, Zhang ZY, Fu XY, Shou W. Zhang W, et al. Among authors: zhang zy, zhang x. J Biol Chem. 2009 Aug 14;284(33):22353-22363. doi: 10.1074/jbc.M109.020495. Epub 2009 Jun 9. J Biol Chem. 2009. PMID: 19509418 Free PMC article.
Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation.
Zhu G, Xie J, Kong W, Xie J, Li Y, Du L, Zheng Q, Sun L, Guan M, Li H, Zhu T, He H, Liu Z, Xia X, Kan C, Tao Y, Shen HC, Li D, Wang S, Yu Y, Yu ZH, Zhang ZY, Liu C, Zhu J. Zhu G, et al. Among authors: zhang zy. Cell. 2020 Oct 15;183(2):490-502.e18. doi: 10.1016/j.cell.2020.09.002. Epub 2020 Sep 30. Cell. 2020. PMID: 33002410 Free PMC article.
SHP2 is a target of the immunosuppressant tautomycetin.
Liu S, Yu Z, Yu X, Huang SX, Luo Y, Wu L, Shen W, Yang Z, Wang L, Gunawan AM, Chan RJ, Shen B, Zhang ZY. Liu S, et al. Among authors: zhang zy. Chem Biol. 2011 Jan 28;18(1):101-10. doi: 10.1016/j.chembiol.2010.10.015. Chem Biol. 2011. PMID: 21276943 Free PMC article.
Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance.
Loh K, Fukushima A, Zhang X, Galic S, Briggs D, Enriori PJ, Simonds S, Wiede F, Reichenbach A, Hauser C, Sims NA, Bence KK, Zhang S, Zhang ZY, Kahn BB, Neel BG, Andrews ZB, Cowley MA, Tiganis T. Loh K, et al. Cell Metab. 2011 Nov 2;14(5):684-99. doi: 10.1016/j.cmet.2011.09.011. Epub 2011 Oct 13. Cell Metab. 2011. PMID: 22000926 Free PMC article.
109,856 results
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