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Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation.
Sharma GG, Hwang KK, Pandita RK, Gupta A, Dhar S, Parenteau J, Agarwal M, Worman HJ, Wellinger RJ, Pandita TK. Sharma GG, et al. Among authors: pandita tk, pandita rk. Mol Cell Biol. 2003 Nov;23(22):8363-76. doi: 10.1128/MCB.23.22.8363-8376.2003. Mol Cell Biol. 2003. PMID: 14585993 Free PMC article.
Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair.
Pandita RK, Sharma GG, Laszlo A, Hopkins KM, Davey S, Chakhparonian M, Gupta A, Wellinger RJ, Zhang J, Powell SN, Roti Roti JL, Lieberman HB, Pandita TK. Pandita RK, et al. Among authors: pandita tk. Mol Cell Biol. 2006 Mar;26(5):1850-64. doi: 10.1128/MCB.26.5.1850-1864.2006. Mol Cell Biol. 2006. PMID: 16479004 Free PMC article.
A role for the HOXB7 homeodomain protein in DNA repair.
Rubin E, Wu X, Zhu T, Cheung JC, Chen H, Lorincz A, Pandita RK, Sharma GG, Ha HC, Gasson J, Hanakahi LA, Pandita TK, Sukumar S. Rubin E, et al. Among authors: pandita tk, pandita rk. Cancer Res. 2007 Feb 15;67(4):1527-35. doi: 10.1158/0008-5472.CAN-06-4283. Cancer Res. 2007. PMID: 17308091
Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status.
Hunt CR, Pandita RK, Laszlo A, Higashikubo R, Agarwal M, Kitamura T, Gupta A, Rief N, Horikoshi N, Baskaran R, Lee JH, Löbrich M, Paull TT, Roti Roti JL, Pandita TK. Hunt CR, et al. Among authors: pandita tk, pandita rk. Cancer Res. 2007 Apr 1;67(7):3010-7. doi: 10.1158/0008-5472.CAN-06-4328. Cancer Res. 2007. PMID: 17409407
The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis.
Gupta A, Guerin-Peyrou TG, Sharma GG, Park C, Agarwal M, Ganju RK, Pandita S, Choi K, Sukumar S, Pandita RK, Ludwig T, Pandita TK. Gupta A, et al. Among authors: pandita s, pandita tk, pandita rk. Mol Cell Biol. 2008 Jan;28(1):397-409. doi: 10.1128/MCB.01045-07. Epub 2007 Oct 29. Mol Cell Biol. 2008. PMID: 17967868 Free PMC article.
Single-stranded DNA-binding protein hSSB1 is critical for genomic stability.
Richard DJ, Bolderson E, Cubeddu L, Wadsworth RI, Savage K, Sharma GG, Nicolette ML, Tsvetanov S, McIlwraith MJ, Pandita RK, Takeda S, Hay RT, Gautier J, West SC, Paull TT, Pandita TK, White MF, Khanna KK. Richard DJ, et al. Among authors: pandita tk, pandita rk. Nature. 2008 May 29;453(7195):677-81. doi: 10.1038/nature06883. Epub 2008 Apr 30. Nature. 2008. PMID: 18449195
206 results