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Canonical and kinase activity-independent mechanisms for extracellular signal-regulated kinase 5 (ERK5) nuclear translocation require dissociation of Hsp90 from the ERK5-Cdc37 complex.
Erazo T, Moreno A, Ruiz-Babot G, Rodríguez-Asiain A, Morrice NA, Espadamala J, Bayascas JR, Gómez N, Lizcano JM. Erazo T, et al. Among authors: gomez n. Mol Cell Biol. 2013 Apr;33(8):1671-86. doi: 10.1128/MCB.01246-12. Epub 2013 Feb 19. Mol Cell Biol. 2013. PMID: 23428871 Free PMC article.
Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains.
Wang J, Erazo T, Ferguson FM, Buckley DL, Gomez N, Muñoz-Guardiola P, Diéguez-Martínez N, Deng X, Hao M, Massefski W, Fedorov O, Offei-Addo NK, Park PM, Dai L, DiBona A, Becht K, Kim ND, McKeown MR, Roberts JM, Zhang J, Sim T, Alessi DR, Bradner JE, Lizcano JM, Blacklow SC, Qi J, Xu X, Gray NS. Wang J, et al. Among authors: gomez n. ACS Chem Biol. 2018 Sep 21;13(9):2438-2448. doi: 10.1021/acschembio.7b00638. Epub 2018 Aug 31. ACS Chem Biol. 2018. PMID: 30102854 Free PMC article.
Alternative ERK5 regulation by phosphorylation during the cell cycle.
Iñesta-Vaquera FA, Campbell DG, Tournier C, Gómez N, Lizcano JM, Cuenda A. Iñesta-Vaquera FA, et al. Among authors: gomez n. Cell Signal. 2010 Dec;22(12):1829-37. doi: 10.1016/j.cellsig.2010.07.010. Epub 2010 Jul 25. Cell Signal. 2010. PMID: 20667468
X-ray crystal structure of ERK5 (MAPK7) in complex with a specific inhibitor.
Elkins JM, Wang J, Deng X, Pattison MJ, Arthur JS, Erazo T, Gomez N, Lizcano JM, Gray NS, Knapp S. Elkins JM, et al. Among authors: gomez n. J Med Chem. 2013 Jun 13;56(11):4413-21. doi: 10.1021/jm4000837. Epub 2013 May 17. J Med Chem. 2013. PMID: 23656407 Free PMC article.
Correction for Zurashvili et al., Interaction of PDK1 with Phosphoinositides Is Essential for Neuronal Differentiation but Dispensable for Neuronal Survival.
Zurashvili T, Cordón-Barris L, Ruiz-Babot G, Zhou X, Lizcano JM, Gómez N, Giménez-Llort L, Bayascas JR. Zurashvili T, et al. Among authors: gomez n. Mol Cell Biol. 2016 May 31;36(12):1818. doi: 10.1128/MCB.00085-16. Print 2016 Jun 15. Mol Cell Biol. 2016. PMID: 27247313 Free PMC article. No abstract available.
639 results