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Reply to Liu et al.: Loss of TGF-β signaling in CARASIL pathogenesis.
Beaufort N, Scharrer E, Lux V, Ehrmann M, Haffner C, Dichgans M. Beaufort N, et al. Among authors: ehrmann m. Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1694. doi: 10.1073/pnas.1501817112. Epub 2015 Mar 13. Proc Natl Acad Sci U S A. 2015. PMID: 25770223 Free PMC article. No abstract available.
Epigenetic silencing of serine protease HTRA1 drives polyploidy.
Schmidt N, Irle I, Ripkens K, Lux V, Nelles J, Johannes C, Parry L, Greenow K, Amir S, Campioni M, Baldi A, Oka C, Kawaichi M, Clarke AR, Ehrmann M. Schmidt N, et al. Among authors: ehrmann m. BMC Cancer. 2016 Jul 7;16:399. doi: 10.1186/s12885-016-2425-8. BMC Cancer. 2016. PMID: 27388476 Free PMC article.
An allosteric HTRA1-calpain 2 complex with restricted activation profile.
Rey J, Breiden M, Lux V, Bluemke A, Steindel M, Ripkens K, Möllers B, Bravo Rodriguez K, Boisguerin P, Volkmer R, Mieres-Perez J, Clausen T, Sanchez-Garcia E, Ehrmann M. Rey J, et al. Among authors: ehrmann m. Proc Natl Acad Sci U S A. 2022 Apr 5;119(14):e2113520119. doi: 10.1073/pnas.2113520119. Epub 2022 Mar 29. Proc Natl Acad Sci U S A. 2022. PMID: 35349341 Free PMC article.
Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration.
Tiaden AN, Klawitter M, Lux V, Mirsaidi A, Bahrenberg G, Glanz S, Quero L, Liebscher T, Wuertz K, Ehrmann M, Richards PJ. Tiaden AN, et al. Among authors: ehrmann m. J Biol Chem. 2012 Jun 15;287(25):21335-45. doi: 10.1074/jbc.M112.341032. Epub 2012 May 3. J Biol Chem. 2012. PMID: 22556410 Free PMC article. Clinical Trial.
Determinants of regulated proteolysis in signal transduction.
Hasenbein S, Merdanovic M, Ehrmann M. Hasenbein S, et al. Among authors: ehrmann m. Genes Dev. 2007 Jan 1;21(1):6-10. doi: 10.1101/gad.1507807. Genes Dev. 2007. PMID: 17210784 Free article. Review. No abstract available.
Protein quality control in the bacterial periplasm.
Merdanovic M, Clausen T, Kaiser M, Huber R, Ehrmann M. Merdanovic M, et al. Among authors: ehrmann m. Annu Rev Microbiol. 2011;65:149-68. doi: 10.1146/annurev-micro-090110-102925. Annu Rev Microbiol. 2011. PMID: 21639788 Review.
Conversion of a regulatory into a degradative protease.
Hasenbein S, Meltzer M, Hauske P, Kaiser M, Huber R, Clausen T, Ehrmann M. Hasenbein S, et al. Among authors: ehrmann m. J Mol Biol. 2010 Apr 9;397(4):957-66. doi: 10.1016/j.jmb.2010.02.027. Epub 2010 Feb 22. J Mol Biol. 2010. PMID: 20184896
235 results