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Sequential C-H Arylation and Enantioselective Hydrogenation Enables Ideal Asymmetric Entry to the Indenopiperidine Core of an 11β-HSD-1 Inhibitor.
Wei X, Qu B, Zeng X, Savoie J, Fandrick KR, Desrosiers JN, Tcyrulnikov S, Marsini MA, Buono FG, Li Z, Yang BS, Tang W, Haddad N, Gutierrez O, Wang J, Lee H, Ma S, Campbell S, Lorenz JC, Eckhardt M, Himmelsbach F, Peters S, Patel ND, Tan Z, Yee NK, Song JJ, Roschangar F, Kozlowski MC, Senanayake CH. Wei X, et al. Among authors: tan z. J Am Chem Soc. 2016 Nov 30;138(47):15473-15481. doi: 10.1021/jacs.6b09764. Epub 2016 Nov 17. J Am Chem Soc. 2016. PMID: 27794616 Free PMC article.
Copper catalyzed asymmetric propargylation of aldehydes.
Fandrick DR, Fandrick KR, Reeves JT, Tan Z, Tang W, Capacci AG, Rodriguez S, Song JJ, Lee H, Yee NK, Senanayake CH. Fandrick DR, et al. Among authors: tan z. J Am Chem Soc. 2010 Jun 9;132(22):7600-1. doi: 10.1021/ja103312x. J Am Chem Soc. 2010. PMID: 20481453
5,893 results