Weldon SM - Search Results

1

Elevated Steroid Hormone Production in the db/db Mouse Model of Obesity and Type 2 Diabetes.

Hofmann A, Peitzsch M, Brunssen C, Mittag J, Jannasch A, Frenzel A, Brown N, Weldon SM, Eisenhofer G, Bornstein SR, Morawietz H. Hofmann A, et al. Among authors: weldon sm. Horm Metab Res. 2017 Jan;49(1):43-49. doi: 10.1055/s-0042-116157. Epub 2016 Nov 3. Horm Metab Res. 2017. PMID: 27813053

2

The Aldosterone Synthase Inhibitor FAD286 is Suitable for Lowering Aldosterone Levels in ZDF Rats but not in db/db Mice.

Hofmann A, Brunssen C, Peitzsch M, Balyura M, Mittag J, Frenzel A, Jannasch A, Brown NF, Weldon SM, Gueneva-Boucheva KK, Eisenhofer G, Bornstein SR, Morawietz H. Hofmann A, et al. Among authors: weldon sm. Horm Metab Res. 2017 Jun;49(6):466-471. doi: 10.1055/s-0043-101821. Epub 2017 Apr 20. Horm Metab Res. 2017. PMID: 28427090

3

Impact of Aldosterone Synthase Inhibitor FAD286 on Steroid Hormone Profile in Human Adrenocortical Cells.

Brunssen C, Hofmann A, Peitzsch M, Frenzel A, Ziegler CG, Brown NF, Weldon SM, Eisenhofer G, Willenberg HS, Bornstein SR, Morawietz H. Brunssen C, et al. Among authors: weldon sm. Horm Metab Res. 2017 Sep;49(9):701-706. doi: 10.1055/s-0043-113829. Epub 2017 Jul 31. Horm Metab Res. 2017. PMID: 28759940

4

Impact of Dietary Sodium Reduction on the Development of Obesity and Type 2 Diabetes in db/db Mice.

Hofmann A, Brunssen C, Peitzsch M, Mittag J, Frenzel A, Eisenhofer G, Brown NF, Weldon SM, Reeps C, Bornstein SR, Morawietz H. Hofmann A, et al. Among authors: weldon sm. Horm Metab Res. 2021 Oct;53(10):699-704. doi: 10.1055/a-1625-6296. Epub 2021 Oct 4. Horm Metab Res. 2021. PMID: 34607368

5

Aldosterone Synthase Inhibition Improves Glucose Tolerance in Zucker Diabetic Fatty (ZDF) Rats.

Hofmann A, Brunssen C, Peitzsch M, Martin M, Mittag J, Jannasch A, Engelmann F, Brown NF, Weldon SM, Huber J, Streicher R, Deussen A, Eisenhofer G, Bornstein SR, Morawietz H. Hofmann A, et al. Among authors: weldon sm. Endocrinology. 2016 Oct;157(10):3844-3855. doi: 10.1210/en.2016-1358. Epub 2016 Aug 15. Endocrinology. 2016. PMID: 27526033

6

Inhibitors of Aldosterone Synthase.

Weldon SM, Brown NF. Weldon SM, et al. Vitam Horm. 2019;109:211-239. doi: 10.1016/bs.vh.2018.10.002. Epub 2018 Dec 21. Vitam Horm. 2019. PMID: 30678857 Review.

7

Selectivity of BI 689648, a Novel, Highly Selective Aldosterone Synthase Inhibitor: Comparison with FAD286 and LCI699 in Nonhuman Primates.

Weldon SM, Cerny MA, Gueneva-Boucheva K, Cogan D, Guo X, Moss N, Parmentier JH, Richman JR, Reinhart GA, Brown NF. Weldon SM, et al. J Pharmacol Exp Ther. 2016 Oct;359(1):142-50. doi: 10.1124/jpet.116.236463. Epub 2016 Aug 1. J Pharmacol Exp Ther. 2016. PMID: 27481775

8

Dihydrobenzisoxazole-4-one compounds are novel selective inhibitors of aldosterone synthase (CYP11B2) with in vivo activity.

Meyers K, Cogan DA, Burke J, Arenas R, Balestra M, Brown NF, Chen Z, Cerny MA, Clifford HE, Colombo F, Fader L, Frederick KS, Guo X, Goldberg D, Hornberger KR, Kugler S, Lord J, Marshall DR, Moss N, Parmentier JH, Richman JR, Schmenk J, Weldon SM, Yu M, Zhang M. Meyers K, et al. Among authors: weldon sm. Bioorg Med Chem Lett. 2018 Mar 1;28(5):979-984. doi: 10.1016/j.bmcl.2017.12.015. Epub 2017 Dec 8. Bioorg Med Chem Lett. 2018. PMID: 29254646

9

Quantification and Comparison of Anti-Fibrotic Therapies by Polarized SRM and SHG-Based Morphometry in Rat UUO Model.

Qian HS, Weldon SM, Matera D, Lee C, Yang H, Fryer RM, Fogo AB, Reinhart GA. Qian HS, et al. Among authors: weldon sm. PLoS One. 2016 Jun 3;11(6):e0156734. doi: 10.1371/journal.pone.0156734. eCollection 2016. PLoS One. 2016. PMID: 27257917 Free PMC article.

10

Differential effects of L-NAME on blood pressure and heart rate responses to acetylcholine and bradykinin in cynomolgus primates.

Weldon SM, Winquist RJ, Madwed JB. Weldon SM, et al. J Pharmacol Exp Ther. 1995 Jan;272(1):126-33. J Pharmacol Exp Ther. 1995. PMID: 7529307

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