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A Druggable TCF4- and BRD4-Dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm.
Ceribelli M, Hou ZE, Kelly PN, Huang DW, Wright G, Ganapathi K, Evbuomwan MO, Pittaluga S, Shaffer AL, Marcucci G, Forman SJ, Xiao W, Guha R, Zhang X, Ferrer M, Chaperot L, Plumas J, Jaffe ES, Thomas CJ, Reizis B, Staudt LM. Ceribelli M, et al. Among authors: shaffer al. Cancer Cell. 2016 Nov 14;30(5):764-778. doi: 10.1016/j.ccell.2016.10.002. Cancer Cell. 2016. PMID: 27846392 Free PMC article.
Signatures of the immune response.
Shaffer AL, Rosenwald A, Hurt EM, Giltnane JM, Lam LT, Pickeral OK, Staudt LM. Shaffer AL, et al. Immunity. 2001 Sep;15(3):375-85. doi: 10.1016/s1074-7613(01)00194-7. Immunity. 2001. PMID: 11567628 Free article. Review.
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation.
Shaffer AL, Shapiro-Shelef M, Iwakoshi NN, Lee AH, Qian SB, Zhao H, Yu X, Yang L, Tan BK, Rosenwald A, Hurt EM, Petroulakis E, Sonenberg N, Yewdell JW, Calame K, Glimcher LH, Staudt LM. Shaffer AL, et al. Immunity. 2004 Jul;21(1):81-93. doi: 10.1016/j.immuni.2004.06.010. Immunity. 2004. PMID: 15345222 Free article.
71 results