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Page 1
In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration.
Suzuki K, Tsunekawa Y, Hernandez-Benitez R, Wu J, Zhu J, Kim EJ, Hatanaka F, Yamamoto M, Araoka T, Li Z, Kurita M, Hishida T, Li M, Aizawa E, Guo S, Chen S, Goebl A, Soligalla RD, Qu J, Jiang T, Fu X, Jafari M, Esteban CR, Berggren WT, Lajara J, Nuñez-Delicado E, Guillen P, Campistol JM, Matsuzaki F, Liu GH, Magistretti P, Zhang K, Callaway EM, Zhang K, Belmonte JC. Suzuki K, et al. Nature. 2016 Dec 1;540(7631):144-149. doi: 10.1038/nature20565. Epub 2016 Nov 16. Nature. 2016. PMID: 27851729 Free PMC article.
In vivo reprogramming of wound-resident cells generates skin epithelial tissue.
Kurita M, Araoka T, Hishida T, O'Keefe DD, Takahashi Y, Sakamoto A, Sakurai M, Suzuki K, Wu J, Yamamoto M, Hernandez-Benitez R, Ocampo A, Reddy P, Shokhirev MN, Magistretti P, Núñez Delicado E, Eto H, Harii K, Izpisua Belmonte JC. Kurita M, et al. Nature. 2018 Sep;561(7722):243-247. doi: 10.1038/s41586-018-0477-4. Epub 2018 Sep 5. Nature. 2018. PMID: 30185909 Free PMC article.
Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction.
Suzuki K, Yamamoto M, Hernandez-Benitez R, Li Z, Wei C, Soligalla RD, Aizawa E, Hatanaka F, Kurita M, Reddy P, Ocampo A, Hishida T, Sakurai M, Nemeth AN, Nuñez Delicado E, Campistol JM, Magistretti P, Guillen P, Rodriguez Esteban C, Gong J, Yuan Y, Gu Y, Liu GH, López-Otín C, Wu J, Zhang K, Izpisua Belmonte JC. Suzuki K, et al. Cell Res. 2019 Oct;29(10):804-819. doi: 10.1038/s41422-019-0213-0. Epub 2019 Aug 23. Cell Res. 2019. PMID: 31444470 Free PMC article.
Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing.
Yuan B, Zhou X, Suzuki K, Ramos-Mandujano G, Wang M, Tehseen M, Cortés-Medina LV, Moresco JJ, Dunn S, Hernandez-Benitez R, Hishida T, Kim NY, Andijani MM, Bi C, Ku M, Takahashi Y, Xu J, Qiu J, Huang L, Benner C, Aizawa E, Qu J, Liu GH, Li Z, Yi F, Ghosheh Y, Shao C, Shokhirev M, Comoli P, Frassoni F, Yates JR 3rd, Fu XD, Esteban CR, Hamdan S, Izpisua Belmonte JC, Li M. Yuan B, et al. Among authors: hernandez benitez r. Nat Commun. 2022 Jun 25;13(1):3646. doi: 10.1038/s41467-022-31220-8. Nat Commun. 2022. PMID: 35752626 Free PMC article.
Author Correction: Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing.
Yuan B, Zhou X, Suzuki K, Ramos-Mandujano G, Wang M, Tehseen M, Cortés-Medina LV, Moresco JJ, Dunn S, Hernandez-Benitez R, Hishida T, Kim NY, Andijani MM, Bi C, Ku M, Takahashi Y, Xu J, Qiu J, Huang L, Benner C, Aizawa E, Qu J, Liu GH, Li Z, Yi F, Ghosheh Y, Shao C, Shokhirev M, Comoli P, Frassoni F, Yates JR 3rd, Fu XD, Esteban CR, Hamdan S, Izpisua Belmonte JC, Li M. Yuan B, et al. Among authors: hernandez benitez r. Nat Commun. 2022 Sep 8;13(1):5291. doi: 10.1038/s41467-022-32875-z. Nat Commun. 2022. PMID: 36075901 Free PMC article. No abstract available.
At the Heart of Genome Editing and Cardiovascular Diseases.
Hernandez-Benitez R, Martinez-Martinez ML, Lajara J, Magistretti P, Montserrat N, Izpisua Belmonte JC. Hernandez-Benitez R, et al. Circ Res. 2018 Jul 6;123(2):221-223. doi: 10.1161/CIRCRESAHA.118.312676. Circ Res. 2018. PMID: 29976689 Review. No abstract available.
αKLOTHO and sTGFβR2 treatment counteract the osteoarthritic phenotype developed in a rat model.
Martinez-Redondo P, Guillen-Guillen I, Davidsohn N, Wang C, Prieto J, Kurita M, Hatanaka F, Zhong C, Hernandez-Benitez R, Hishida T, Lezaki T, Sakamoto A, Nemeth AN, Hishida Y, Esteban CR, Shojima K, Huang L, Shokhirev M, Nuñez-Delicado E, Campistol JM, Guillen-Vicente I, Rodriguez-Iñigo E, Lopez-Alcorocho JM, Guillen-Vicente M, Church G, Reddy P, Guillen-Garcia P, Liu GH, Belmonte JCI. Martinez-Redondo P, et al. Protein Cell. 2020 Mar;11(3):219-226. doi: 10.1007/s13238-019-00685-7. Protein Cell. 2020. PMID: 31950348 Free PMC article. No abstract available.
First progeria monkey model generated using base editor.
Reddy P, Shao Y, Hernandez-Benitez R, Nuñez Delicado E, Izpisua Belmonte JC. Reddy P, et al. Protein Cell. 2020 Dec;11(12):862-865. doi: 10.1007/s13238-020-00765-z. Protein Cell. 2020. PMID: 32729023 Free PMC article. Review. No abstract available.
40 results