Nickels ML - Search Results

1

Evaluation of TSPO PET Ligands [¹⁸F]VUIIS1009A and [¹⁸F]VUIIS1009B: Tracers for Cancer Imaging.

Tang D, Li J, Buck JR, Tantawy MN, Xia Y, Harp JM, Nickels ML, Meiler J, Manning HC. Tang D, et al. Among authors: nickels ml. Mol Imaging Biol. 2017 Aug;19(4):578-588. doi: 10.1007/s11307-016-1027-9. Mol Imaging Biol. 2017. PMID: 27853987 Free PMC article.

2

Synthesis and structure-activity relationships of 5,6,7-substituted pyrazolopyrimidines: discovery of a novel TSPO PET ligand for cancer imaging.

Tang D, McKinley ET, Hight MR, Uddin MI, Harp JM, Fu A, Nickels ML, Buck JR, Manning HC. Tang D, et al. Among authors: nickels ml. J Med Chem. 2013 Apr 25;56(8):3429-33. doi: 10.1021/jm4001874. Epub 2013 Apr 3. J Med Chem. 2013. PMID: 23521048 Free PMC article.

3

Preclinical imaging evaluation of novel TSPO-PET ligand 2-(5,7-Diethyl-2-(4-(2-[(18)F]fluoroethoxy)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamide ([ (18)F]VUIIS1008) in glioma.

Tang D, Nickels ML, Tantawy MN, Buck JR, Manning HC. Tang D, et al. Among authors: nickels ml. Mol Imaging Biol. 2014 Dec;16(6):813-20. doi: 10.1007/s11307-014-0743-2. Mol Imaging Biol. 2014. PMID: 24845529 Free PMC article.

4

Facile synthesis of SSR180575 and discovery of 7-chloro-N,N,5-trimethyl-4-oxo-3(6-[(18)F]fluoropyridin-2-yl)-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide, a potent pyridazinoindole ligand for PET imaging of TSPO in cancer.

Cheung YY, Nickels ML, Tang D, Buck JR, Manning HC. Cheung YY, et al. Among authors: nickels ml. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4466-4471. doi: 10.1016/j.bmcl.2014.07.091. Epub 2014 Aug 8. Bioorg Med Chem Lett. 2014. PMID: 25172419 Free PMC article.

5

Preclinical Evaluation of 4-[18F]Fluoroglutamine PET to Assess ASCT2 Expression in Lung Cancer.

Hassanein M, Hight MR, Buck JR, Tantawy MN, Nickels ML, Hoeksema MD, Harris BK, Boyd K, Massion PP, Manning HC. Hassanein M, et al. Among authors: nickels ml. Mol Imaging Biol. 2016 Feb;18(1):18-23. doi: 10.1007/s11307-015-0862-4. Mol Imaging Biol. 2016. PMID: 25971659 Free PMC article.

6

Utility of [¹⁸F]FSPG PET to Image Hepatocellular Carcinoma: First Clinical Evaluation in a US Population.

Kavanaugh G, Williams J, Morris AS, Nickels ML, Walker R, Koglin N, Stephens AW, Washington MK, Geevarghese SK, Liu Q, Ayers D, Shyr Y, Manning HC. Kavanaugh G, et al. Among authors: nickels ml. Mol Imaging Biol. 2016 Dec;18(6):924-934. doi: 10.1007/s11307-016-1007-0. Mol Imaging Biol. 2016. PMID: 27677886 Free PMC article. Clinical Trial.

7

Preclinical Evaluation of a Novel TSPO PET Ligand 2-(7-Butyl-2-(4-(2-[¹⁸F]Fluoroethoxy)phenyl)-5-Methylpyrazolo[1,5-a]Pyrimidin-3-yl)-N,N-Diethylacetamide (¹⁸F-VUIIS1018A) to Image Glioma.

Tang D, Li J, Nickels ML, Huang G, Cohen AS, Manning HC. Tang D, et al. Among authors: nickels ml. Mol Imaging Biol. 2019 Feb;21(1):113-121. doi: 10.1007/s11307-018-1198-7. Mol Imaging Biol. 2019. PMID: 29869061 Free PMC article.

8

The Current Role of Microfluidics in Radiofluorination Chemistry.

Knapp KA, Nickels ML, Manning HC. Knapp KA, et al. Among authors: nickels ml. Mol Imaging Biol. 2020 Jun;22(3):463-475. doi: 10.1007/s11307-019-01414-6. Mol Imaging Biol. 2020. PMID: 31485889 Review.

9

Quantitative preclinical imaging of TSPO expression in glioma using N,N-diethyl-2-(2-(4-(2-18F-fluoroethoxy)phenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide.

Tang D, Hight MR, McKinley ET, Fu A, Buck JR, Smith RA, Tantawy MN, Peterson TE, Colvin DC, Ansari MS, Nickels M, Manning HC. Tang D, et al. J Nucl Med. 2012 Feb;53(2):287-94. doi: 10.2967/jnumed.111.095653. Epub 2012 Jan 17. J Nucl Med. 2012. PMID: 22251555 Free PMC article.

10

PET radiotracer [¹⁸F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: preliminary investigation.

Perrone MG, Malerba P, Uddin J, Vitale P, Panella A, Crews BC, Daniel CK, Ghebreselasie K, Nickels M, Tantawy MN, Manning HC, Marnett LJ, Scilimati A. Perrone MG, et al. Eur J Med Chem. 2014 Jun 10;80:562-568. doi: 10.1016/j.ejmech.2014.04.074. Epub 2014 Apr 29. Eur J Med Chem. 2014. PMID: 24832612 Free PMC article.

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