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Elucidating the interplay between IgG-Fc valency and FcγR activation for the design of immune complex inhibitors.
Ortiz DF, Lansing JC, Rutitzky L, Kurtagic E, Prod'homme T, Choudhury A, Washburn N, Bhatnagar N, Beneduce C, Holte K, Prenovitz R, Child M, Killough J, Tyler S, Brown J, Nguyen S, Schwab I, Hains M, Meccariello R, Markowitz L, Wang J, Zouaoui R, Simpson A, Schultes B, Capila I, Ling L, Nimmerjahn F, Manning AM, Bosques CJ. Ortiz DF, et al. Among authors: simpson a. Sci Transl Med. 2016 Nov 16;8(365):365ra158. doi: 10.1126/scitranslmed.aaf9418. Sci Transl Med. 2016. PMID: 27856797
Selective inhibition of TGFβ1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape.
Martin CJ, Datta A, Littlefield C, Kalra A, Chapron C, Wawersik S, Dagbay KB, Brueckner CT, Nikiforov A, Danehy FT Jr, Streich FC Jr, Boston C, Simpson A, Jackson JW, Lin S, Danek N, Faucette RR, Raman P, Capili AD, Buckler A, Carven GJ, Schürpf T. Martin CJ, et al. Among authors: simpson a. Sci Transl Med. 2020 Mar 25;12(536):eaay8456. doi: 10.1126/scitranslmed.aay8456. Sci Transl Med. 2020. PMID: 32213632
Childhood lung function is associated with adolescent-onset and persistent asthma.
Koefoed HJL, Ullah A, Hallberg J, Merid SK, Kere MM, Lowe L, Simpson A, Murray CS, Gehring U, Vermeulen R, Kull I, Bergström A, Vonk JM, Custovic A, Melén E, Koppelman GH. Koefoed HJL, et al. Among authors: simpson a. ERJ Open Res. 2024 Dec 9;10(6):00469-2024. doi: 10.1183/23120541.00469-2024. eCollection 2024 Nov. ERJ Open Res. 2024. PMID: 39655169 Free PMC article.
Neobacillus driksii sp. nov. isolated from a Mars 2020 spacecraft assembly facility and genomic potential for lasso peptide production in Neobacillus.
Hameed A, McDonagh F, Sengupta P, Miliotis G, Sivabalan SKM, Szydlowski L, Simpson A, Singh NK, Rekha PD, Raman K, Venkateswaran K. Hameed A, et al. Among authors: simpson a. Microbiol Spectr. 2024 Nov 29:e0137624. doi: 10.1128/spectrum.01376-24. Online ahead of print. Microbiol Spectr. 2024. PMID: 39611829 Free article.
3,357 results