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A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands.
Qin T, Barron L, Xia L, Huang H, Villarreal MM, Zwaagstra J, Collins C, Yang J, Zwieb C, Kodali R, Hinck CS, Kim SK, Reddick RL, Shu C, O'Connor-McCourt MD, Hinck AP, Sun LZ. Qin T, et al. Among authors: o connor mccourt md. Oncotarget. 2016 Dec 27;7(52):86087-86102. doi: 10.18632/oncotarget.13343. Oncotarget. 2016. PMID: 27863384 Free PMC article.
Binding Properties of the Transforming Growth Factor-β Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling.
Villarreal MM, Kim SK, Barron L, Kodali R, Baardsnes J, Hinck CS, Krzysiak TC, Henen MA, Pakhomova O, Mendoza V, O'Connor-McCourt MD, Lafer EM, López-Casillas F, Hinck AP. Villarreal MM, et al. Among authors: o connor mccourt md. Biochemistry. 2016 Dec 13;55(49):6880-6896. doi: 10.1021/acs.biochem.6b00566. Epub 2016 Dec 2. Biochemistry. 2016. PMID: 27951653 Free PMC article.
Correction: A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands.
Qin T, Barron L, Xia L, Huang H, Villarreal MM, Zwaagstra J, Collins C, Yang J, Zwieb C, Kodali R, Hinck CS, Kim SK, Reddick RL, Shu C, O'Connor-McCourt MD, Hinck AP, Sun LZ. Qin T, et al. Among authors: o connor mccourt md. Oncotarget. 2017 Aug 21;8(34):57905. doi: 10.18632/oncotarget.20370. eCollection 2017 Aug 22. Oncotarget. 2017. PMID: 28915722 Free PMC article.
Engineering and therapeutic application of single-chain bivalent TGF-β family traps.
Zwaagstra JC, Sulea T, Baardsnes J, Lenferink AE, Collins C, Cantin C, Paul-Roc B, Grothe S, Hossain S, Richer LP, L'Abbé D, Tom R, Cass B, Durocher Y, O'Connor-McCourt MD. Zwaagstra JC, et al. Among authors: o connor mccourt md. Mol Cancer Ther. 2012 Jul;11(7):1477-87. doi: 10.1158/1535-7163.MCT-12-0060. Epub 2012 May 4. Mol Cancer Ther. 2012. PMID: 22562986
109 results