Purroy N - Search Results

1

Inhibition of BCR signaling using the Syk inhibitor TAK-659 prevents stroma-mediated signaling in chronic lymphocytic leukemia cells.

Purroy N, Carabia J, Abrisqueta P, Egia L, Aguiló M, Carpio C, Palacio C, Crespo M, Bosch F. Purroy N, et al. Oncotarget. 2017 Jan 3;8(1):742-756. doi: 10.18632/oncotarget.13557. Oncotarget. 2017. PMID: 27888629 Free PMC article.

2

Targeting the proliferative and chemoresistant compartment in chronic lymphocytic leukemia by inhibiting survivin protein.

Purroy N, Abrisqueta P, Carabia J, Carpio C, Calpe E, Palacio C, Castellví J, Crespo M, Bosch F. Purroy N, et al. Leukemia. 2014 Oct;28(10):1993-2004. doi: 10.1038/leu.2014.96. Epub 2014 Mar 12. Leukemia. 2014. PMID: 24618734

3

ZAP-70 enhances migration of malignant B lymphocytes toward CCL21 by inducing CCR7 expression via IgM-ERK1/2 activation.

Calpe E, Codony C, Baptista MJ, Abrisqueta P, Carpio C, Purroy N, Bosch F, Crespo M. Calpe E, et al. Among authors: purroy n. Blood. 2011 Oct 20;118(16):4401-10. doi: 10.1182/blood-2011-01-333682. Epub 2011 Aug 24. Blood. 2011. PMID: 21865343 Free article.

4

ZAP-70 promotes the infiltration of malignant B-lymphocytes into the bone marrow by enhancing signaling and migration after CXCR4 stimulation.

Calpe E, Purroy N, Carpio C, Abrisqueta P, Carabia J, Palacio C, Castellví J, Crespo M, Bosch F. Calpe E, et al. Among authors: purroy n. PLoS One. 2013 Dec 3;8(12):e81221. doi: 10.1371/journal.pone.0081221. eCollection 2013. PLoS One. 2013. PMID: 24312539 Free PMC article.

5

Co-culture of primary CLL cells with bone marrow mesenchymal cells, CD40 ligand and CpG ODN promotes proliferation of chemoresistant CLL cells phenotypically comparable to those proliferating in vivo.

Purroy N, Abrisqueta P, Carabia J, Carpio C, Palacio C, Bosch F, Crespo M. Purroy N, et al. Oncotarget. 2015 Apr 10;6(10):7632-43. doi: 10.18632/oncotarget.2939. Oncotarget. 2015. PMID: 25544766 Free PMC article.

6

Microenvironment regulates the expression of miR-21 and tumor suppressor genes PTEN, PIAS3 and PDCD4 through ZAP-70 in chronic lymphocytic leukemia.

Carabia J, Carpio C, Abrisqueta P, Jiménez I, Purroy N, Calpe E, Palacio C, Bosch F, Crespo M. Carabia J, et al. Among authors: purroy n. Sci Rep. 2017 Sep 25;7(1):12262. doi: 10.1038/s41598-017-12135-7. Sci Rep. 2017. PMID: 28947822 Free PMC article.

7

Repolarization of tumor infiltrating macrophages and increased survival in mouse primary CNS lymphomas after XPO1 and BTK inhibition.

Jiménez I, Carabia J, Bobillo S, Palacio C, Abrisqueta P, Pagès C, Nieto JC, Castellví J, Martínez-Ricarte F, Escoda L, Perla C, Céspedes Torrez DH, Boix J, Purroy N, Puigdefàbregas L, Seoane J, Bosch F, Crespo M. Jiménez I, et al. Among authors: purroy n. J Neurooncol. 2020 Aug;149(1):13-25. doi: 10.1007/s11060-020-03580-y. Epub 2020 Jul 20. J Neurooncol. 2020. PMID: 32691208 Free PMC article.

8

Preneoplastic Alterations Define CLL DNA Methylome and Persist through Disease Progression and Therapy.

Kretzmer H, Biran A, Purroy N, Lemvigh CK, Clement K, Gruber M, Gu H, Rassenti L, Mohammad AW, Lesnick C, Slager SL, Braggio E, Shanafelt TD, Kay NE, Fernandes SM, Brown JR, Wang L, Li S, Livak KJ, Neuberg DS, Klages S, Timmermann B, Kipps TJ, Campo E, Gnirke A, Wu CJ, Meissner A. Kretzmer H, et al. Among authors: purroy n. Blood Cancer Discov. 2021 Jan;2(1):54-69. doi: 10.1158/2643-3230.BCD-19-0058. Epub 2020 Dec 3. Blood Cancer Discov. 2021. PMID: 33604581 Free PMC article.

9

Coevolution of Leukemia and Host Immune Cells in Chronic Lymphocytic Leukemia.

Purroy N, Wu CJ. Purroy N, et al. Cold Spring Harb Perspect Med. 2017 Apr 3;7(4):a026740. doi: 10.1101/cshperspect.a026740. Cold Spring Harb Perspect Med. 2017. PMID: 28096240 Free PMC article. Review.

10

Long-term follow-up of dose-adjusted EPOCH plus rituximab (DA-EPOCH-R) in untreated patients with poor prognosis large B-cell lymphoma. A phase II study conducted by the Spanish PETHEMA Group.

Purroy N, Bergua J, Gallur L, Prieto J, Lopez LA, Sancho JM, García-Marco JA, Castellví J, Montes-Moreno S, Batlle A, de Villambrosia SG, Carnicero F, Ferrando-Lamana L, Piris MA, Lopez A. Purroy N, et al. Br J Haematol. 2015 Apr;169(2):188-98. doi: 10.1111/bjh.13273. Epub 2014 Dec 18. Br J Haematol. 2015. PMID: 25521006 Free article. Clinical Trial.

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