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Page 1
Enantiomeric resolution of a novel chiral cannabinoid receptor ligand.
Thakur GA, Palmer SL, Harrington PE, Stergiades IA, Tius MA, Makriyannis A. Thakur GA, et al. Among authors: makriyannis a. J Biochem Biophys Methods. 2002 Dec 31;54(1-3):415-22. doi: 10.1016/s0165-022x(02)00144-6. J Biochem Biophys Methods. 2002. PMID: 12543516
CB1 cannabinoid receptor ligands.
Thakur GA, Nikas SP, Makriyannis A. Thakur GA, et al. Among authors: makriyannis a. Mini Rev Med Chem. 2005 Jul;5(7):631-40. doi: 10.2174/1389557054368772. Mini Rev Med Chem. 2005. PMID: 16026309 Review.
(-)-7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahydrocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptor.
Picone RP, Khanolkar AD, Xu W, Ayotte LA, Thakur GA, Hurst DP, Abood ME, Reggio PH, Fournier DJ, Makriyannis A. Picone RP, et al. Among authors: makriyannis a. Mol Pharmacol. 2005 Dec;68(6):1623-35. doi: 10.1124/mol.105.014407. Epub 2005 Sep 12. Mol Pharmacol. 2005. PMID: 16157695
Methods for the synthesis of cannabinergic ligands.
Thakur GA, Nikas SP, Duclos RI Jr, Makriyannis A. Thakur GA, et al. Among authors: makriyannis a. Methods Mol Med. 2006;123:113-48. doi: 10.1385/1-59259-999-0:113. Methods Mol Med. 2006. PMID: 16506405
Structural requirements for cannabinoid receptor probes.
Thakur GA, Nikas SP, Li C, Makriyannis A. Thakur GA, et al. Among authors: makriyannis a. Handb Exp Pharmacol. 2005;(168):209-46. doi: 10.1007/3-540-26573-2_7. Handb Exp Pharmacol. 2005. PMID: 16596776 Review.
Cannabinoid receptors as therapeutic targets.
Pavlopoulos S, Thakur GA, Nikas SP, Makriyannis A. Pavlopoulos S, et al. Among authors: makriyannis a. Curr Pharm Des. 2006;12(14):1751-69. doi: 10.2174/138161206776873743. Curr Pharm Des. 2006. PMID: 16712486 Review.
519 results