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Large-scale pharmacological profiling of 3D tumor models of cancer cells.
Mathews Griner LA, Zhang X, Guha R, McKnight C, Goldlust IS, Lal-Nag M, Wilson K, Michael S, Titus S, Shinn P, Thomas CJ, Ferrer M. Mathews Griner LA, et al. Among authors: shinn p. Cell Death Dis. 2016 Dec 1;7(12):e2492. doi: 10.1038/cddis.2016.360. Cell Death Dis. 2016. PMID: 27906188 Free PMC article.
Fluorescence spectroscopic profiling of compound libraries.
Simeonov A, Jadhav A, Thomas CJ, Wang Y, Huang R, Southall NT, Shinn P, Smith J, Austin CP, Auld DS, Inglese J. Simeonov A, et al. Among authors: shinn p. J Med Chem. 2008 Apr 24;51(8):2363-71. doi: 10.1021/jm701301m. Epub 2008 Mar 26. J Med Chem. 2008. PMID: 18363325
Compound Management for Quantitative High-Throughput Screening.
Yasgar A, Shinn P, Jadhav A, Auld D, Michael S, Zheng W, Austin CP, Inglese J, Simeonov A. Yasgar A, et al. Among authors: shinn p. JALA Charlottesv Va. 2008 Apr;13(2):79-89. doi: 10.1016/j.jala.2007.12.004. JALA Charlottesv Va. 2008. PMID: 18496600 Free PMC article.
Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma.
Yang Y, Shaffer AL 3rd, Emre NC, Ceribelli M, Zhang M, Wright G, Xiao W, Powell J, Platig J, Kohlhammer H, Young RM, Zhao H, Yang Y, Xu W, Buggy JJ, Balasubramanian S, Mathews LA, Shinn P, Guha R, Ferrer M, Thomas C, Waldmann TA, Staudt LM. Yang Y, et al. Among authors: shinn p. Cancer Cell. 2012 Jun 12;21(6):723-37. doi: 10.1016/j.ccr.2012.05.024. Cancer Cell. 2012. PMID: 22698399 Free PMC article.
Multiplexing high-content flow (HCF) and quantitative high-throughput screening (qHTS) to identify compounds capable of decreasing cell viability, activating caspase 3/7, expressing annexin V, and changing mitochondrial membrane integrity.
Mathews LA, Keller JM, McKnight C, Michael S, Shinn P, Liu D, Staudt LM, Thomas CJ, Ferrer M. Mathews LA, et al. Among authors: shinn p. Curr Protoc Chem Biol. 2013;5(3):195-212. doi: 10.1002/9780470559277.ch130060. Curr Protoc Chem Biol. 2013. PMID: 24391083
98 results