Grandjean CL - Search Results

1

Heterogeneous yet stable Vδ2(+) T-cell profiles define distinct cytotoxic effector potentials in healthy human individuals.

Ryan PL, Sumaria N, Holland CJ, Bradford CM, Izotova N, Grandjean CL, Jawad AS, Bergmeier LA, Pennington DJ. Ryan PL, et al. Among authors: grandjean cl. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14378-14383. doi: 10.1073/pnas.1611098113. Epub 2016 Nov 28. Proc Natl Acad Sci U S A. 2016. PMID: 27911793 Free PMC article.

2

Strong TCRγδ Signaling Prohibits Thymic Development of IL-17A-Secreting γδ T Cells.

Sumaria N, Grandjean CL, Silva-Santos B, Pennington DJ. Sumaria N, et al. Among authors: grandjean cl. Cell Rep. 2017 Jun 20;19(12):2469-2476. doi: 10.1016/j.celrep.2017.05.071. Cell Rep. 2017. PMID: 28636936 Free PMC article.

3

Increased TCR signal strength in DN thymocytes promotes development of gut TCRαβ⁽⁺⁾CD8αα⁽⁺⁾ intraepithelial lymphocytes.

Grandjean CL, Sumaria N, Martin S, Pennington DJ. Grandjean CL, et al. Sci Rep. 2017 Sep 6;7(1):10659. doi: 10.1038/s41598-017-09368-x. Sci Rep. 2017. PMID: 28878277 Free PMC article.

4

A cross-talk between CAR T cell subsets and the tumor microenvironment is essential for sustained cytotoxic activity.

Boulch M, Cazaux M, Loe-Mie Y, Thibaut R, Corre B, Lemaître F, Grandjean CL, Garcia Z, Bousso P. Boulch M, et al. Among authors: grandjean cl. Sci Immunol. 2021 Mar 26;6(57):eabd4344. doi: 10.1126/sciimmunol.abd4344. Sci Immunol. 2021. PMID: 33771887 Free article.

5

Single-cell imaging of CAR T cell activity in vivo reveals extensive functional and anatomical heterogeneity.

Cazaux M, Grandjean CL, Lemaître F, Garcia Z, Beck RJ, Milo I, Postat J, Beltman JB, Cheadle EJ, Bousso P. Cazaux M, et al. Among authors: grandjean cl. J Exp Med. 2019 May 6;216(5):1038-1049. doi: 10.1084/jem.20182375. Epub 2019 Apr 1. J Exp Med. 2019. PMID: 30936262 Free PMC article.

6

Tumor Immunosurveillance and Immunotherapies: A Fresh Look from Intravital Imaging.

Boulch M, Grandjean CL, Cazaux M, Bousso P. Boulch M, et al. Among authors: grandjean cl. Trends Immunol. 2019 Nov;40(11):1022-1034. doi: 10.1016/j.it.2019.09.002. Epub 2019 Oct 23. Trends Immunol. 2019. PMID: 31668676 Review.

7

Imaging the mechanisms of anti-CD20 therapy in vivo uncovers spatiotemporal bottlenecks in antibody-dependent phagocytosis.

Grandjean CL, Garcia Z, Lemaître F, Bréart B, Bousso P. Grandjean CL, et al. Sci Adv. 2021 Feb 19;7(8):eabd6167. doi: 10.1126/sciadv.abd6167. Print 2021 Feb. Sci Adv. 2021. PMID: 33608271 Free PMC article.

8

Intravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodies.

Grandjean CL, Montalvao F, Celli S, Michonneau D, Breart B, Garcia Z, Perro M, Freytag O, Gerdes CA, Bousso P. Grandjean CL, et al. Sci Rep. 2016 Oct 4;6:34382. doi: 10.1038/srep34382. Sci Rep. 2016. PMID: 27698437 Free PMC article.

9

Anti-PD-1 therapy triggers Tfh cell-dependent IL-4 release to boost CD8 T cell responses in tumor-draining lymph nodes.

Ruggiu M, Guérin MV, Corre B, Bardou M, Alonso R, Russo E, Garcia Z, Feldmann L, Lemaître F, Dusseaux M, Grandjean CL, Bousso P. Ruggiu M, et al. Among authors: grandjean cl. J Exp Med. 2024 Apr 1;221(4):e20232104. doi: 10.1084/jem.20232104. Epub 2024 Feb 28. J Exp Med. 2024. PMID: 38417020 Free PMC article.

10

Tumor-intrinsic sensitivity to the pro-apoptotic effects of IFN-γ is a major determinant of CD4⁺ CAR T-cell antitumor activity.

Boulch M, Cazaux M, Cuffel A, Guerin MV, Garcia Z, Alonso R, Lemaître F, Beer A, Corre B, Menger L, Grandjean CL, Morin F, Thieblemont C, Caillat-Zucman S, Bousso P. Boulch M, et al. Among authors: grandjean cl. Nat Cancer. 2023 Jul;4(7):968-983. doi: 10.1038/s43018-023-00570-7. Epub 2023 May 29. Nat Cancer. 2023. PMID: 37248395 Free PMC article.

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