Brem R - Search Results

1

A genome-wide screen of bacterial mutants that enhance dauer formation in C. elegans.

Khanna A, Kumar J, Vargas MA, Barrett L, Katewa S, Li P, McCloskey T, Sharma A, Naudé N, Nelson C, Brem R, Killilea DW, Mooney SD, Gill M, Kapahi P. Khanna A, et al. Among authors: brem r. Sci Rep. 2016 Dec 13;6:38764. doi: 10.1038/srep38764. Sci Rep. 2016. PMID: 27958277 Free PMC article.

2

Peripheral Circadian Clocks Mediate Dietary Restriction-Dependent Changes in Lifespan and Fat Metabolism in Drosophila.

Katewa SD, Akagi K, Bose N, Rakshit K, Camarella T, Zheng X, Hall D, Davis S, Nelson CS, Brem RB, Ramanathan A, Sehgal A, Giebultowicz JM, Kapahi P. Katewa SD, et al. Cell Metab. 2016 Jan 12;23(1):143-54. doi: 10.1016/j.cmet.2015.10.014. Epub 2015 Nov 25. Cell Metab. 2016. PMID: 26626459 Free PMC article.

3

Vitamin D Promotes Protein Homeostasis and Longevity via the Stress Response Pathway Genes skn-1, ire-1, and xbp-1.

Mark KA, Dumas KJ, Bhaumik D, Schilling B, Davis S, Oron TR, Sorensen DJ, Lucanic M, Brem RB, Melov S, Ramanathan A, Gibson BW, Lithgow GJ. Mark KA, et al. Cell Rep. 2016 Oct 25;17(5):1227-1237. doi: 10.1016/j.celrep.2016.09.086. Cell Rep. 2016. PMID: 27783938 Free PMC article.

4

Cross-phenotype association tests uncover genes mediating nutrient response in Drosophila.

Nelson CS, Beck JN, Wilson KA, Pilcher ER, Kapahi P, Brem RB. Nelson CS, et al. Among authors: brem rb. BMC Genomics. 2016 Nov 4;17(1):867. doi: 10.1186/s12864-016-3137-9. BMC Genomics. 2016. PMID: 27809764 Free PMC article.

5

Potassium restriction boosts vacuolar acidity and extends lifespan in yeast.

Sasikumar AN, Killilea DW, Kennedy BK, Brem RB. Sasikumar AN, et al. Exp Gerontol. 2019 Jun;120:101-106. doi: 10.1016/j.exger.2019.02.001. Epub 2019 Feb 8. Exp Gerontol. 2019. PMID: 30742903 Free PMC article.

6

GWAS for Lifespan and Decline in Climbing Ability in Flies upon Dietary Restriction Reveal decima as a Mediator of Insulin-like Peptide Production.

Wilson KA, Beck JN, Nelson CS, Hilsabeck TA, Promislow D, Brem RB, Kapahi P. Wilson KA, et al. Curr Biol. 2020 Jul 20;30(14):2749-2760.e3. doi: 10.1016/j.cub.2020.05.020. Epub 2020 Jun 4. Curr Biol. 2020. PMID: 32502405 Free PMC article.

7

Genetic and metabolomic architecture of variation in diet restriction-mediated lifespan extension in Drosophila.

Jin K, Wilson KA, Beck JN, Nelson CS, Brownridge GW 3rd, Harrison BR, Djukovic D, Raftery D, Brem RB, Yu S, Drton M, Shojaie A, Kapahi P, Promislow D. Jin K, et al. Among authors: brem rb. PLoS Genet. 2020 Jul 9;16(7):e1008835. doi: 10.1371/journal.pgen.1008835. eCollection 2020 Jul. PLoS Genet. 2020. PMID: 32644988 Free PMC article.

8

Musashi expression in intestinal stem cells attenuates radiation-induced decline in intestinal permeability and survival in Drosophila.

Sharma A, Akagi K, Pattavina B, Wilson KA, Nelson C, Watson M, Maksoud E, Harata A, Ortega M, Brem RB, Kapahi P. Sharma A, et al. Sci Rep. 2020 Nov 5;10(1):19080. doi: 10.1038/s41598-020-75867-z. Sci Rep. 2020. PMID: 33154387 Free PMC article.

9

Trimethylamine modulates dauer formation, neurodegeneration, and lifespan through tyra-3/daf-11 signaling in Caenorhabditis elegans.

Khanna A, Sellegounder D, Kumar J, Chamoli M, Vargas M, Chinta SJ, Rane A, Nelson C, Peiris TH, Brem R, Andersen J, Lithgow G, Kapahi P. Khanna A, et al. Among authors: brem r. Aging Cell. 2021 May;20(5):e13351. doi: 10.1111/acel.13351. Epub 2021 Apr 5. Aging Cell. 2021. PMID: 33819374 Free PMC article.

10

A fly GWAS for purine metabolites identifies human FAM214 homolog medusa, which acts in a conserved manner to enhance hyperuricemia-driven pathologies by modulating purine metabolism and the inflammatory response.

Hilsabeck TAU, Liu-Bryan R, Guo T, Wilson KA, Bose N, Raftery D, Beck JN, Lang S, Jin K, Nelson CS, Oron T, Stoller M, Promislow D, Brem RB, Terkeltaub R, Kapahi P. Hilsabeck TAU, et al. Among authors: brem rb. Geroscience. 2022 Aug;44(4):2195-2211. doi: 10.1007/s11357-022-00557-9. Epub 2022 Apr 6. Geroscience. 2022. PMID: 35381951 Free PMC article.

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