Darling DS - Search Results

1

ZEB1-induced tumourigenesis requires senescence inhibition via activation of DKK1/mutant p53/Mdm2/CtBP and repression of macroH2A1.

de Barrios O, Győrffy B, Fernández-Aceñero MJ, Sánchez-Tilló E, Sánchez-Moral L, Siles L, Esteve-Arenys A, Roué G, Casal JI, Darling DS, Castells A, Postigo A. de Barrios O, et al. Among authors: darling ds. Gut. 2017 Apr;66(4):666-682. doi: 10.1136/gutjnl-2015-310838. Epub 2016 Dec 13. Gut. 2017. PMID: 27965283

2

ZEB1 and TCF4 reciprocally modulate their transcriptional activities to regulate Wnt target gene expression.

Sánchez-Tilló E, de Barrios O, Valls E, Darling DS, Castells A, Postigo A. Sánchez-Tilló E, et al. Among authors: darling ds. Oncogene. 2015 Nov 12;34(46):5760-70. doi: 10.1038/onc.2015.352. Epub 2015 Sep 21. Oncogene. 2015. PMID: 26387539

3

ZEB1 imposes a temporary stage-dependent inhibition of muscle gene expression and differentiation via CtBP-mediated transcriptional repression.

Siles L, Sánchez-Tilló E, Lim JW, Darling DS, Kroll KL, Postigo A. Siles L, et al. Among authors: darling ds. Mol Cell Biol. 2013 Apr;33(7):1368-82. doi: 10.1128/MCB.01259-12. Epub 2013 Jan 22. Mol Cell Biol. 2013. PMID: 23339872 Free PMC article.

4

ZEB1 Promotes invasiveness of colorectal carcinoma cells through the opposing regulation of uPA and PAI-1.

Sánchez-Tilló E, de Barrios O, Siles L, Amendola PG, Darling DS, Cuatrecasas M, Castells A, Postigo A. Sánchez-Tilló E, et al. Among authors: darling ds. Clin Cancer Res. 2013 Mar 1;19(5):1071-82. doi: 10.1158/1078-0432.CCR-12-2675. Epub 2013 Jan 22. Clin Cancer Res. 2013. PMID: 23340304

5

Tumor-associated macrophages (TAMs) depend on ZEB1 for their cancer-promoting roles.

Cortés M, Sanchez-Moral L, de Barrios O, Fernández-Aceñero MJ, Martínez-Campanario MC, Esteve-Codina A, Darling DS, Győrffy B, Lawrence T, Dean DC, Postigo A. Cortés M, et al. Among authors: darling ds. EMBO J. 2017 Nov 15;36(22):3336-3355. doi: 10.15252/embj.201797345. Epub 2017 Oct 16. EMBO J. 2017. PMID: 29038174 Free PMC article.

6

Regulation of muscle atrophy-related genes by the opposing transcriptional activities of ZEB1/CtBP and FOXO3.

Ninfali C, Siles L, Darling DS, Postigo A. Ninfali C, et al. Among authors: darling ds. Nucleic Acids Res. 2018 Nov 16;46(20):10697-10708. doi: 10.1093/nar/gky835. Nucleic Acids Res. 2018. PMID: 30304480 Free PMC article.

7

ZEB1 promotes inflammation and progression towards inflammation-driven carcinoma through repression of the DNA repair glycosylase MPG in epithelial cells.

de Barrios O, Sanchez-Moral L, Cortés M, Ninfali C, Profitós-Pelejà N, Martínez-Campanario MC, Siles L, Del Campo R, Fernández-Aceñero MJ, Darling DS, Castells A, Maurel J, Salas A, Dean DC, Postigo A. de Barrios O, et al. Among authors: darling ds. Gut. 2019 Dec;68(12):2129-2141. doi: 10.1136/gutjnl-2018-317294. Epub 2019 Jul 31. Gut. 2019. PMID: 31366457

8

EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness.

Sánchez-Tilló E, Liu Y, de Barrios O, Siles L, Fanlo L, Cuatrecasas M, Darling DS, Dean DC, Castells A, Postigo A. Sánchez-Tilló E, et al. Among authors: darling ds. Cell Mol Life Sci. 2012 Oct;69(20):3429-56. doi: 10.1007/s00018-012-1122-2. Epub 2012 Sep 4. Cell Mol Life Sci. 2012. PMID: 22945800 Free PMC article. Review.

9

Different thresholds of ZEB1 are required for Ras-mediated tumour initiation and metastasis.

Liu Y, Lu X, Huang L, Wang W, Jiang G, Dean KC, Clem B, Telang S, Jenson AB, Cuatrecasas M, Chesney J, Darling DS, Postigo A, Dean DC. Liu Y, et al. Among authors: darling ds. Nat Commun. 2014 Dec 1;5:5660. doi: 10.1038/ncomms6660. Nat Commun. 2014. PMID: 25434817 Free article.

10

ZEB1 protects skeletal muscle from damage and is required for its regeneration.

Siles L, Ninfali C, Cortés M, Darling DS, Postigo A. Siles L, et al. Among authors: darling ds. Nat Commun. 2019 Mar 25;10(1):1364. doi: 10.1038/s41467-019-08983-8. Nat Commun. 2019. PMID: 30910999 Free PMC article.

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