Verbrugge I - Search Results

1

Dermal Delivery of Constructs Encoding Cre Recombinase to Induce Skin Tumors in Pten^LoxP/LoxP;Braf^CA/+ Mice.

Deken MA, Song JY, Gadiot J, Bins AD, Kroon P, Verbrugge I, Blank CU. Deken MA, et al. Among authors: verbrugge i. Int J Mol Sci. 2016 Dec 20;17(12):2149. doi: 10.3390/ijms17122149. Int J Mol Sci. 2016. PMID: 27999416 Free PMC article.

2

Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma.

Kroon P, Gadiot J, Peeters M, Gasparini A, Deken MA, Yagita H, Verheij M, Borst J, Blank CU, Verbrugge I. Kroon P, et al. Among authors: verbrugge i. Cancer Immunol Immunother. 2016 Jun;65(6):753-63. doi: 10.1007/s00262-016-1843-4. Epub 2016 May 9. Cancer Immunol Immunother. 2016. PMID: 27160390 Free PMC article.

3

Targeting the MAPK and PI3K pathways in combination with PD1 blockade in melanoma.

Deken MA, Gadiot J, Jordanova ES, Lacroix R, van Gool M, Kroon P, Pineda C, Geukes Foppen MH, Scolyer R, Song JY, Verbrugge I, Hoeller C, Dummer R, Haanen JB, Long GV, Blank CU. Deken MA, et al. Among authors: verbrugge i. Oncoimmunology. 2016 Oct 14;5(12):e1238557. doi: 10.1080/2162402X.2016.1238557. eCollection 2016. Oncoimmunology. 2016. PMID: 28123875 Free PMC article.

4

Radiotherapy and Cisplatin Increase Immunotherapy Efficacy by Enabling Local and Systemic Intratumoral T-cell Activity.

Kroon P, Frijlink E, Iglesias-Guimarais V, Volkov A, van Buuren MM, Schumacher TN, Verheij M, Borst J, Verbrugge I. Kroon P, et al. Among authors: verbrugge i. Cancer Immunol Res. 2019 Apr;7(4):670-682. doi: 10.1158/2326-6066.CIR-18-0654. Epub 2019 Feb 19. Cancer Immunol Res. 2019. PMID: 30782666

5

The curative outcome of radioimmunotherapy in a mouse breast cancer model relies on mTOR signaling.

Verbrugge I, Gasparini A, Haynes NM, Hagekyriakou J, Galli M, Stewart TJ, Abrams SI, Yagita H, Verheij M, Johnstone RW, Borst J, Neefjes J. Verbrugge I, et al. Radiat Res. 2014 Aug;182(2):219-29. doi: 10.1667/RR13511.1. Epub 2014 Jun 24. Radiat Res. 2014. PMID: 24960417

6

Smac/DIABLO release from mitochondria and XIAP inhibition are essential to limit clonogenicity of Type I tumor cells after TRAIL receptor stimulation.

Maas C, Verbrugge I, de Vries E, Savich G, van de Kooij LW, Tait SW, Borst J. Maas C, et al. Among authors: verbrugge i. Cell Death Differ. 2010 Oct;17(10):1613-23. doi: 10.1038/cdd.2010.39. Epub 2010 Apr 16. Cell Death Differ. 2010. PMID: 20395960

7

Combination Approaches with Immune-Checkpoint Blockade in Cancer Therapy.

Swart M, Verbrugge I, Beltman JB. Swart M, et al. Among authors: verbrugge i. Front Oncol. 2016 Nov 1;6:233. doi: 10.3389/fonc.2016.00233. eCollection 2016. Front Oncol. 2016. PMID: 27847783 Free PMC article. Review.

8

TRAIL enhances efficacy of radiotherapy in a p53 mutant, Bcl-2 overexpressing lymphoid malignancy.

Wissink EH, Verbrugge I, Vink SR, Schader MB, Schaefer U, Walczak H, Borst J, Verheij M. Wissink EH, et al. Among authors: verbrugge i. Radiother Oncol. 2006 Aug;80(2):214-22. doi: 10.1016/j.radonc.2006.07.030. Epub 2006 Aug 17. Radiother Oncol. 2006. PMID: 16916556

9

Combining radiotherapy with APO010 in cancer treatment.

Verbrugge I, Wissink EH, Rooswinkel RW, Jongsma J, Beltraminelli N, Dupuis M, Borst J, Verheij M. Verbrugge I, et al. Clin Cancer Res. 2009 Mar 15;15(6):2031-8. doi: 10.1158/1078-0432.CCR-08-2125. Epub 2009 Mar 10. Clin Cancer Res. 2009. PMID: 19276268

10

Radiation and anticancer drugs can facilitate mitochondrial bypass by CD95/Fas via c-FLIP downregulation.

Verbrugge I, Maas C, Heijkoop M, Verheij M, Borst J. Verbrugge I, et al. Cell Death Differ. 2010 Mar;17(3):551-61. doi: 10.1038/cdd.2009.141. Epub 2009 Oct 2. Cell Death Differ. 2010. PMID: 19798106

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