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Page 1
WNT Signaling in Lung Aging and Disease.
Lehmann M, Baarsma HA, Königshoff M. Lehmann M, et al. Among authors: baarsma ha. Ann Am Thorac Soc. 2016 Dec;13 Suppl 5:S411-S416. doi: 10.1513/AnnalsATS.201608-586AW. Ann Am Thorac Soc. 2016. PMID: 28005418 Review.
WNT receptor signalling in lung physiology and pathology.
Skronska-Wasek W, Gosens R, Königshoff M, Baarsma HA. Skronska-Wasek W, et al. Among authors: baarsma ha. Pharmacol Ther. 2018 Jul;187:150-166. doi: 10.1016/j.pharmthera.2018.02.009. Epub 2018 Feb 17. Pharmacol Ther. 2018. PMID: 29458107 Review.
Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD.
Baarsma HA, Skronska-Wasek W, Mutze K, Ciolek F, Wagner DE, John-Schuster G, Heinzelmann K, Günther A, Bracke KR, Dagouassat M, Boczkowski J, Brusselle GG, Smits R, Eickelberg O, Yildirim AÖ, Königshoff M. Baarsma HA, et al. J Exp Med. 2017 Jan;214(1):143-163. doi: 10.1084/jem.20160675. Epub 2016 Dec 15. J Exp Med. 2017. PMID: 27979969 Free PMC article.
Reduced Frizzled Receptor 4 Expression Prevents WNT/β-Catenin-driven Alveolar Lung Repair in Chronic Obstructive Pulmonary Disease.
Skronska-Wasek W, Mutze K, Baarsma HA, Bracke KR, Alsafadi HN, Lehmann M, Costa R, Stornaiuolo M, Novellino E, Brusselle GG, Wagner DE, Yildirim AÖ, Königshoff M. Skronska-Wasek W, et al. Among authors: baarsma ha. Am J Respir Crit Care Med. 2017 Jul 15;196(2):172-185. doi: 10.1164/rccm.201605-0904OC. Am J Respir Crit Care Med. 2017. PMID: 28245136
Increased Extracellular Vesicles Mediate WNT5A Signaling in Idiopathic Pulmonary Fibrosis.
Martin-Medina A, Lehmann M, Burgy O, Hermann S, Baarsma HA, Wagner DE, De Santis MM, Ciolek F, Hofer TP, Frankenberger M, Aichler M, Lindner M, Gesierich W, Guenther A, Walch A, Coughlan C, Wolters P, Lee JS, Behr J, Königshoff M. Martin-Medina A, et al. Among authors: baarsma ha. Am J Respir Crit Care Med. 2018 Dec 15;198(12):1527-1538. doi: 10.1164/rccm.201708-1580OC. Am J Respir Crit Care Med. 2018. PMID: 30044642
A drug screen with approved compounds identifies amlexanox as a novel Wnt/β-catenin activator inducing lung epithelial organoid formation.
Costa R, Wagner DE, Doryab A, De Santis MM, Schorpp K, Rothenaigner I, Lehmann M, Baarsma HA, Liu X, Schmid O, Campillos M, Yildirim AÖ, Hadian K, Königshoff M. Costa R, et al. Among authors: baarsma ha. Br J Pharmacol. 2021 Oct;178(19):4026-4041. doi: 10.1111/bph.15581. Epub 2021 Jul 31. Br J Pharmacol. 2021. PMID: 34089180 Free PMC article.
32 results