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Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn.
Hasumi H, Baba M, Hasumi Y, Lang M, Huang Y, Oh HF, Matsuo M, Merino MJ, Yao M, Ito Y, Furuya M, Iribe Y, Kodama T, Southon E, Tessarollo L, Nagashima K, Haines DC, Linehan WM, Schmidt LS. Hasumi H, et al. Among authors: hasumi y. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1624-31. doi: 10.1073/pnas.1419502112. Epub 2015 Mar 16. Proc Natl Acad Sci U S A. 2015. PMID: 25775561 Free PMC article.
H255Y and K508R missense mutations in tumour suppressor folliculin (FLCN) promote kidney cell proliferation.
Hasumi H, Hasumi Y, Baba M, Nishi H, Furuya M, Vocke CD, Lang M, Irie N, Esumi C, Merino MJ, Kawahara T, Isono Y, Makiyama K, Warner AC, Haines DC, Wei MH, Zbar B, Hagenau H, Feigenbaum L, Kondo K, Nakaigawa N, Yao M, Metwalli AR, Marston Linehan W, Schmidt LS. Hasumi H, et al. Among authors: hasumi y. Hum Mol Genet. 2017 Jan 15;26(2):354-366. doi: 10.1093/hmg/ddw392. Hum Mol Genet. 2017. PMID: 28007907 Free PMC article.
BHD-associated kidney cancer exhibits unique molecular characteristics and a wide variety of variants in chromatin remodeling genes.
Hasumi H, Furuya M, Tatsuno K, Yamamoto S, Baba M, Hasumi Y, Isono Y, Suzuki K, Jikuya R, Otake S, Muraoka K, Osaka K, Hayashi N, Makiyama K, Miyoshi Y, Kondo K, Nakaigawa N, Kawahara T, Izumi K, Teranishi J, Yumura Y, Uemura H, Nagashima Y, Metwalli AR, Schmidt LS, Aburatani H, Linehan WM, Yao M. Hasumi H, et al. Among authors: hasumi y. Hum Mol Genet. 2018 Aug 1;27(15):2712-2724. doi: 10.1093/hmg/ddy181. Hum Mol Genet. 2018. PMID: 29767721 Free PMC article.
Folliculin Regulates Osteoclastogenesis Through Metabolic Regulation.
Baba M, Endoh M, Ma W, Toyama H, Hirayama A, Nishikawa K, Takubo K, Hano H, Hasumi H, Umemoto T, Hashimoto M, Irie N, Esumi C, Kataoka M, Nakagata N, Soga T, Yao M, Kamba T, Minami T, Ishii M, Suda T. Baba M, et al. Among authors: hasumi h. J Bone Miner Res. 2018 Oct;33(10):1785-1798. doi: 10.1002/jbmr.3477. Epub 2018 Jun 26. J Bone Miner Res. 2018. PMID: 29893999 Free PMC article.
122 results