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Page 1
SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b.
Kugel S, Sebastián C, Fitamant J, Ross KN, Saha SK, Jain E, Gladden A, Arora KS, Kato Y, Rivera MN, Ramaswamy S, Sadreyev RI, Goren A, Deshpande V, Bardeesy N, Mostoslavsky R. Kugel S, et al. Among authors: ramaswamy s. Cell. 2016 Jun 2;165(6):1401-1415. doi: 10.1016/j.cell.2016.04.033. Epub 2016 May 12. Cell. 2016. PMID: 27180906 Free PMC article.
REDD1 loss reprograms lipid metabolism to drive progression of RAS mutant tumors.
Qiao S, Koh SB, Vivekanandan V, Salunke D, Patra KC, Zaganjor E, Ross K, Mizukami Y, Jeanfavre S, Chen A, Mino-Kenudson M, Ramaswamy S, Clish C, Haigis M, Bardeesy N, Ellisen LW. Qiao S, et al. Among authors: ramaswamy s. Genes Dev. 2020 Jun 1;34(11-12):751-766. doi: 10.1101/gad.335166.119. Epub 2020 Apr 9. Genes Dev. 2020. PMID: 32273287 Free PMC article.
RASAL2 Confers Collateral MEK/EGFR Dependency in Chemoresistant Triple-Negative Breast Cancer.
Koh SB, Ross K, Isakoff SJ, Melkonjan N, He L, Matissek KJ, Schultz A, Mayer EL, Traina TA, Carey LA, Rugo HS, Liu MC, Stearns V, Langenbucher A, Saladi SV, Ramaswamy S, Lawrence MS, Ellisen LW. Koh SB, et al. Among authors: ramaswamy s. Clin Cancer Res. 2021 Sep 1;27(17):4883-4897. doi: 10.1158/1078-0432.CCR-21-0714. Epub 2021 Jun 24. Clin Cancer Res. 2021. PMID: 34168046 Free PMC article.
Aneuploidy and a deregulated DNA damage response suggest haploinsufficiency in breast tissues of BRCA2 mutation carriers.
Karaayvaz-Yildirim M, Silberman RE, Langenbucher A, Saladi SV, Ross KN, Zarcaro E, Desmond A, Yildirim M, Vivekanandan V, Ravichandran H, Mylavagnanam R, Specht MC, Ramaswamy S, Lawrence M, Amon A, Ellisen LW. Karaayvaz-Yildirim M, et al. Among authors: ramaswamy s. Sci Adv. 2020 Jan 29;6(5):eaay2611. doi: 10.1126/sciadv.aay2611. eCollection 2020 Jan. Sci Adv. 2020. PMID: 32064343 Free PMC article.
AKT1low Quiescent Cancer Cells Promote Solid Tumor Growth.
Alves CP, Dey-Guha I, Kabraji S, Yeh AC, Talele NP, Solé X, Chowdhury J, Mino-Kenudson M, Loda M, Sgroi D, Borresen-Dale AL, Russnes HG, Ross KN, Ramaswamy S. Alves CP, et al. Among authors: ramaswamy s. Mol Cancer Ther. 2018 Jan;17(1):254-263. doi: 10.1158/1535-7163.MCT-16-0868. Epub 2017 Oct 20. Mol Cancer Ther. 2018. PMID: 29054988 Free PMC article.
AKT Inhibition Promotes Nonautonomous Cancer Cell Survival.
Salony, Solé X, Alves CP, Dey-Guha I, Ritsma L, Boukhali M, Lee JH, Chowdhury J, Ross KN, Haas W, Vasudevan S, Ramaswamy S. Salony, et al. Among authors: ramaswamy s. Mol Cancer Ther. 2016 Jan;15(1):142-53. doi: 10.1158/1535-7163.MCT-15-0414. Epub 2015 Dec 4. Mol Cancer Ther. 2016. PMID: 26637368 Free PMC article.
Integrin β1 activation induces an anti-melanoma host response.
Ritsma L, Dey-Guha I, Talele N, Sole X, Salony, Chowdhury J, Ross KN, Ramaswamy S. Ritsma L, et al. Among authors: ramaswamy s. PLoS One. 2017 Apr 27;12(4):e0175300. doi: 10.1371/journal.pone.0175300. eCollection 2017. PLoS One. 2017. PMID: 28448494 Free PMC article.
The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.
Etchegaray JP, Chavez L, Huang Y, Ross KN, Choi J, Martinez-Pastor B, Walsh RM, Sommer CA, Lienhard M, Gladden A, Kugel S, Silberman DM, Ramaswamy S, Mostoslavsky G, Hochedlinger K, Goren A, Rao A, Mostoslavsky R. Etchegaray JP, et al. Among authors: ramaswamy s. Nat Cell Biol. 2015 May;17(5):545-57. doi: 10.1038/ncb3147. Epub 2015 Apr 27. Nat Cell Biol. 2015. PMID: 25915124 Free PMC article.
Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism.
Perera RM, Stoykova S, Nicolay BN, Ross KN, Fitamant J, Boukhali M, Lengrand J, Deshpande V, Selig MK, Ferrone CR, Settleman J, Stephanopoulos G, Dyson NJ, Zoncu R, Ramaswamy S, Haas W, Bardeesy N. Perera RM, et al. Among authors: ramaswamy s. Nature. 2015 Aug 20;524(7565):361-5. doi: 10.1038/nature14587. Epub 2015 Jul 13. Nature. 2015. PMID: 26168401 Free PMC article.
876 results