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Proteolytic Origin of the Soluble Human IL-6R In Vivo and a Decisive Role of N-Glycosylation.
Riethmueller S, Somasundaram P, Ehlers JC, Hung CW, Flynn CM, Lokau J, Agthe M, Düsterhöft S, Zhu Y, Grötzinger J, Lorenzen I, Koudelka T, Yamamoto K, Pickhinke U, Wichert R, Becker-Pauly C, Rädisch M, Albrecht A, Hessefort M, Stahnke D, Unverzagt C, Rose-John S, Tholey A, Garbers C. Riethmueller S, et al. Among authors: lorenzen i. PLoS Biol. 2017 Jan 6;15(1):e2000080. doi: 10.1371/journal.pbio.2000080. eCollection 2017 Jan. PLoS Biol. 2017. PMID: 28060820 Free PMC article.
Distance dependent shedding of IL-6R.
Düsterhöft S, Bartels AK, Koudelka T, Lilienthal E, Schäfer M, Garbers C, Tholey A, Grötzinger J, Lorenzen I. Düsterhöft S, et al. Among authors: lorenzen i. Biochem Biophys Res Commun. 2020 May 28;526(2):355-360. doi: 10.1016/j.bbrc.2020.03.093. Epub 2020 Mar 26. Biochem Biophys Res Commun. 2020. PMID: 32222277
Stabilized Interleukin-6 receptor binding RNA aptamers.
Meyer C, Berg K, Eydeler-Haeder K, Lorenzen I, Grötzinger J, Rose-John S, Hahn U. Meyer C, et al. Among authors: lorenzen i. RNA Biol. 2014;11(1):57-65. doi: 10.4161/rna.27447. Epub 2013 Dec 20. RNA Biol. 2014. PMID: 24440854 Free PMC article.
Phosphatidylserine exposure is required for ADAM17 sheddase function.
Sommer A, Kordowski F, Büch J, Maretzky T, Evers A, Andrä J, Düsterhöft S, Michalek M, Lorenzen I, Somasundaram P, Tholey A, Sönnichsen FD, Kunzelmann K, Heinbockel L, Nehls C, Gutsmann T, Grötzinger J, Bhakdi S, Reiss K. Sommer A, et al. Among authors: lorenzen i. Nat Commun. 2016 May 10;7:11523. doi: 10.1038/ncomms11523. Nat Commun. 2016. PMID: 27161080 Free PMC article.
229 results