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26 results

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Page 1
Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex.
Kuzikov M, Reinshagen J, Wycisk K, Corona A, Esposito F, Malune P, Manelfi C, Iaconis D, Beccari A, Tramontano E, Nowotny M, Windshügel B, Gribbon P, Zaliani A. Kuzikov M, et al. Among authors: iaconis d. Virus Res. 2024 May;343:199356. doi: 10.1016/j.virusres.2024.199356. Epub 2024 Mar 16. Virus Res. 2024. PMID: 38490582 Free PMC article.
Diketo acid inhibitors of nsp13 of SARS-CoV-2 block viral replication.
Corona A, Madia VN, De Santis R, Manelfi C, Emmolo R, Ialongo D, Patacchini E, Messore A, Amatore D, Faggioni G, Artico M, Iaconis D, Talarico C, Di Santo R, Lista F, Costi R, Tramontano E. Corona A, et al. Among authors: iaconis d. Antiviral Res. 2023 Sep;217:105697. doi: 10.1016/j.antiviral.2023.105697. Epub 2023 Aug 9. Antiviral Res. 2023. PMID: 37562607 Free article.
Relevance of Spike/Estrogen Receptor-α interaction for endothelial-based coagulopathy induced by SARS-CoV-2.
Barbieri SS, Cattani F, Sandrini L, Grillo MM, Amendola A, Valente C, Talarico C, Iaconis D, Turacchio G, Lucariello M, Lione L, Salvatori E, Amadio P, Garoffolo G, Maffei M, Galli F, Beccari AR, Sberna G, Marra E, Zoppi M, Michaelides M, Roscilli G, Aurisicchio L, Bertini R, Allegretti M, Pesce M. Barbieri SS, et al. Among authors: iaconis d. Signal Transduct Target Ther. 2023 May 19;8(1):203. doi: 10.1038/s41392-023-01488-3. Signal Transduct Target Ther. 2023. PMID: 37208343 Free PMC article. No abstract available.
The SARS-CoV-2 spike protein binds and modulates estrogen receptors.
Solis O, Beccari AR, Iaconis D, Talarico C, Ruiz-Bedoya CA, Nwachukwu JC, Cimini A, Castelli V, Bertini R, Montopoli M, Cocetta V, Borocci S, Prandi IG, Flavahan K, Bahr M, Napiorkowski A, Chillemi G, Ooka M, Yang X, Zhang S, Xia M, Zheng W, Bonaventura J, Pomper MG, Hooper JE, Morales M, Rosenberg AZ, Nettles KW, Jain SK, Allegretti M, Michaelides M. Solis O, et al. Among authors: iaconis d. Sci Adv. 2022 Dec 2;8(48):eadd4150. doi: 10.1126/sciadv.add4150. Epub 2022 Nov 30. Sci Adv. 2022. PMID: 36449624 Free PMC article.
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort.
Zaliani A, Vangeel L, Reinshagen J, Iaconis D, Kuzikov M, Keminer O, Wolf M, Ellinger B, Esposito F, Corona A, Tramontano E, Manelfi C, Herzog K, Jochmans D, De Jonghe S, Chiu W, Francken T, Schepers J, Collard C, Abbasi K, Claussen C, Summa V, Beccari AR, Neyts J, Gribbon P, Leyssen P. Zaliani A, et al. Among authors: iaconis d. Sci Data. 2022 Jul 13;9(1):405. doi: 10.1038/s41597-022-01532-x. Sci Data. 2022. PMID: 35831315 Free PMC article.
The SARS-CoV-2 spike protein binds and modulates estrogen receptors.
Solis O, Beccari AR, Iaconis D, Talarico C, Ruiz-Bedoya CA, Nwachukwu JC, Cimini A, Castelli V, Bertini R, Montopoli M, Cocetta V, Borocci S, Prandi IG, Flavahan K, Bahr M, Napiorkowski A, Chillemi G, Ooka M, Yang X, Zhang S, Xia M, Zheng W, Bonaventura J, Pomper MG, Hooper JE, Morales M, Rosenberg AZ, Nettles KW, Jain SK, Allegretti M, Michaelides M. Solis O, et al. Among authors: iaconis d. bioRxiv [Preprint]. 2022 May 23:2022.05.21.492920. doi: 10.1101/2022.05.21.492920. bioRxiv. 2022. Update in: Sci Adv. 2022 Dec 2;8(48):eadd4150. doi: 10.1126/sciadv.add4150 PMID: 35665018 Free PMC article. Updated. Preprint.
Characterization of raloxifene as a potential pharmacological agent against SARS-CoV-2 and its variants.
Iaconis D, Bordi L, Matusali G, Talarico C, Manelfi C, Cesta MC, Zippoli M, Caccuri F, Bugatti A, Zani A, Filippini F, Scorzolini L, Gobbi M, Beeg M, Piotti A, Montopoli M, Cocetta V, Bressan S, Bucci EM, Caruso A, Nicastri E, Allegretti M, Beccari AR. Iaconis D, et al. Cell Death Dis. 2022 May 25;13(5):498. doi: 10.1038/s41419-022-04961-z. Cell Death Dis. 2022. PMID: 35614039 Free PMC article.
Paclitaxel binds and activates C5aR1: A new potential therapeutic target for the prevention of chemotherapy-induced peripheral neuropathy and hypersensitivity reactions.
Brandolini L, d'Angelo M, Novelli R, Castelli V, Giorgio C, Sirico A, Cocchiaro P, D'Egidio F, Benedetti E, Cristiano C, Bugatti A, Ruocco A, Amendola PG, Talarico C, Manelfi C, Iaconis D, Beccari A, Quadros AU, Cunha TM, Caruso A, Russo R, Cimini A, Aramini A, Allegretti M. Brandolini L, et al. Among authors: iaconis d. Cell Death Dis. 2022 May 25;13(5):500. doi: 10.1038/s41419-022-04964-w. Cell Death Dis. 2022. PMID: 35614037 Free PMC article.
26 results