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The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders.
Chang H, Hoshina N, Zhang C, Ma Y, Cao H, Wang Y, Wu DD, Bergen SE, Landén M, Hultman CM, Preisig M, Kutalik Z, Castelao E, Grigoroiu-Serbanescu M, Forstner AJ, Strohmaier J, Hecker J, Schulze TG, Müller-Myhsok B, Reif A, Mitchell PB, Martin NG, Schofield PR, Cichon S, Nöthen MM; Swedish Bipolar Study Group; MooDS Bipolar Consortium; Walter H, Erk S, Heinz A, Amin N, van Duijn CM, Meyer-Lindenberg A, Tost H, Xiao X, Yamamoto T, Rietschel M, Li M. Chang H, et al. Among authors: zhang c. Mol Psychiatry. 2018 Feb;23(2):400-412. doi: 10.1038/mp.2016.231. Epub 2017 Jan 10. Mol Psychiatry. 2018. PMID: 28070120 Free PMC article.
Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants.
Gamazon ER, Badner JA, Cheng L, Zhang C, Zhang D, Cox NJ, Gershon ES, Kelsoe JR, Greenwood TA, Nievergelt CM, Chen C, McKinney R, Shilling PD, Schork NJ, Smith EN, Bloss CS, Nurnberger JI, Edenberg HJ, Foroud T, Koller DL, Scheftner WA, Coryell W, Rice J, Lawson WB, Nwulia EA, Hipolito M, Byerley W, McMahon FJ, Schulze TG, Berrettini WH, Potash JB, Zandi PP, Mahon PB, McInnis MG, Zöllner S, Zhang P, Craig DW, Szelinger S, Barrett TB, Liu C. Gamazon ER, et al. Among authors: zhang c, zhang p, zhang d. Mol Psychiatry. 2013 Mar;18(3):340-6. doi: 10.1038/mp.2011.174. Epub 2012 Jan 3. Mol Psychiatry. 2013. PMID: 22212596 Free PMC article.
Two gene co-expression modules differentiate psychotics and controls.
Chen C, Cheng L, Grennan K, Pibiri F, Zhang C, Badner JA; Members of the Bipolar Disorder Genome Study (BiGS) Consortium; Gershon ES, Liu C. Chen C, et al. Among authors: zhang c. Mol Psychiatry. 2013 Dec;18(12):1308-14. doi: 10.1038/mp.2012.146. Epub 2012 Nov 13. Mol Psychiatry. 2013. PMID: 23147385 Free PMC article.
Expression of the G72/G30 gene in transgenic mice induces behavioral changes.
Cheng L, Hattori E, Nakajima A, Woehrle NS, Opal MD, Zhang C, Grennan K, Dulawa SC, Tang YP, Gershon ES, Liu C. Cheng L, et al. Among authors: zhang c. Mol Psychiatry. 2014 Feb;19(2):175-83. doi: 10.1038/mp.2012.185. Epub 2013 Jan 22. Mol Psychiatry. 2014. PMID: 23337943 Free PMC article.
Independent replications and integrative analyses confirm TRANK1 as a susceptibility gene for bipolar disorder.
Li W, Cai X, Li HJ, Song M, Zhang CY, Yang Y, Zhang L, Zhao L, Liu W, Wang L, Shao M, Zhang Y, Zhang C, Cai J, Zhou DS, Li X, Hui L, Jia QF, Qu N, Zhong BL, Zhang SF, Chen J, Xia B, Li Y, Song X, Fan W, Tang W, Tang W, Tang J, Chen X, Yue W, Zhang D, Fang Y, Xiao X, Li M, Lv L, Chang H. Li W, et al. Among authors: zhang cy, zhang l, zhang c, zhang d, zhang sf, zhang y. Neuropsychopharmacology. 2021 May;46(6):1103-1112. doi: 10.1038/s41386-020-00788-4. Epub 2020 Aug 13. Neuropsychopharmacology. 2021. PMID: 32791513 Free PMC article.
Novel Risk Loci Associated With Genetic Risk for Bipolar Disorder Among Han Chinese Individuals: A Genome-Wide Association Study and Meta-analysis.
Li HJ, Zhang C, Hui L, Zhou DS, Li Y, Zhang CY, Wang C, Wang L, Li W, Yang Y, Qu N, Tang J, He Y, Zhou J, Yang Z, Li X, Cai J, Yang L, Chen J, Fan W, Tang W, Tang W, Jia QF, Liu W, Zhuo C, Song X, Liu F, Bai Y, Zhong BL, Zhang SF, Chen J, Xia B, Lv L, Liu Z, Hu S, Li XY, Liu JW, Cai X, Yao YG, Zhang Y, Yan H, Chang S, Zhao JP, Yue WH, Luo XJ, Chen X, Xiao X, Fang Y, Li M; GeseDNA Research Team. Li HJ, et al. Among authors: zhang cy, zhang c, zhang sf, zhang y. JAMA Psychiatry. 2021 Mar 1;78(3):320-330. doi: 10.1001/jamapsychiatry.2020.3738. JAMA Psychiatry. 2021. PMID: 33263727 Free PMC article.
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