Kuppusamy P - Search Results

1

Benzyl Isothiocyanate potentiates p53 signaling and antitumor effects against breast cancer through activation of p53-LKB1 and p73-LKB1 axes.

Xie B, Nagalingam A, Kuppusamy P, Muniraj N, Langford P, Győrffy B, Saxena NK, Sharma D. Xie B, et al. Among authors: kuppusamy p. Sci Rep. 2017 Jan 10;7:40070. doi: 10.1038/srep40070. Sci Rep. 2017. PMID: 28071670 Free PMC article.

2

Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3.

Sengupta S, Nagalingam A, Muniraj N, Bonner MY, Mistriotis P, Afthinos A, Kuppusamy P, Lanoue D, Cho S, Korangath P, Shriver M, Begum A, Merino VF, Huang CY, Arbiser JL, Matsui W, Győrffy B, Konstantopoulos K, Sukumar S, Marignani PA, Saxena NK, Sharma D. Sengupta S, et al. Among authors: kuppusamy p. Oncogene. 2017 Oct 12;36(41):5709-5721. doi: 10.1038/onc.2017.164. Epub 2017 Jun 5. Oncogene. 2017. PMID: 28581518 Free PMC article.

3

Mechanistic elucidation of the antitumor properties of withaferin a in breast cancer.

Nagalingam A, Kuppusamy P, Singh SV, Sharma D, Saxena NK. Nagalingam A, et al. Among authors: kuppusamy p. Cancer Res. 2014 May 1;74(9):2617-29. doi: 10.1158/0008-5472.CAN-13-2081. Epub 2014 Apr 14. Cancer Res. 2014. PMID: 24732433 Free PMC article.

4

ADIPOQ/adiponectin induces cytotoxic autophagy in breast cancer cells through STK11/LKB1-mediated activation of the AMPK-ULK1 axis.

Chung SJ, Nagaraju GP, Nagalingam A, Muniraj N, Kuppusamy P, Walker A, Woo J, Győrffy B, Gabrielson E, Saxena NK, Sharma D. Chung SJ, et al. Among authors: kuppusamy p. Autophagy. 2017 Aug 3;13(8):1386-1403. doi: 10.1080/15548627.2017.1332565. Epub 2017 Jul 11. Autophagy. 2017. PMID: 28696138 Free PMC article.

5

Concomitant activation of ETS-like transcription factor-1 and Death Receptor-5 via extracellular signal-regulated kinase in withaferin A-mediated inhibition of hepatocarcinogenesis in mice.

Kuppusamy P, Nagalingam A, Muniraj N, Saxena NK, Sharma D. Kuppusamy P, et al. Sci Rep. 2017 Dec 20;7(1):17943. doi: 10.1038/s41598-017-18190-4. Sci Rep. 2017. PMID: 29263422 Free PMC article.

6

Honokiol abrogates leptin-induced tumor progression by inhibiting Wnt1-MTA1-β-catenin signaling axis in a microRNA-34a dependent manner.

Avtanski DB, Nagalingam A, Kuppusamy P, Bonner MY, Arbiser JL, Saxena NK, Sharma D. Avtanski DB, et al. Among authors: kuppusamy p. Oncotarget. 2015 Jun 30;6(18):16396-410. doi: 10.18632/oncotarget.3844. Oncotarget. 2015. PMID: 26036628 Free PMC article.

7

Hyperleptinemia in obese state renders luminal breast cancers refractory to tamoxifen by coordinating a crosstalk between Med1, miR205 and ErbB.

Nagalingam A, Siddharth S, Parida S, Muniraj N, Avtanski D, Kuppusamy P, Elsey J, Arbiser JL, Győrffy B, Sharma D. Nagalingam A, et al. Among authors: kuppusamy p. NPJ Breast Cancer. 2021 Aug 13;7(1):105. doi: 10.1038/s41523-021-00314-9. NPJ Breast Cancer. 2021. PMID: 34389732 Free PMC article.

8

Metformin Enhances the Anti-Cancer Efficacy of Sorafenib via Suppressing MAPK/ERK/Stat3 Axis in Hepatocellular Carcinoma.

Siddharth S, Kuppusamy P, Wu Q, Nagalingam A, Saxena NK, Sharma D. Siddharth S, et al. Among authors: kuppusamy p. Int J Mol Sci. 2022 Jul 22;23(15):8083. doi: 10.3390/ijms23158083. Int J Mol Sci. 2022. PMID: 35897659 Free PMC article.

9

Interacting post-muscarinic receptor signaling pathways potentiate matrix metalloproteinase-1 expression and invasion of human colon cancer cells.

Said AH, Hu S, Abutaleb A, Watkins T, Cheng K, Chahdi A, Kuppusamy P, Saxena N, Xie G, Raufman JP. Said AH, et al. Among authors: kuppusamy p. Biochem J. 2017 Feb 20;474(5):647-665. doi: 10.1042/BCJ20160704. Biochem J. 2017. PMID: 28008134 Free PMC article.

10

Re-oxygenation causes hypoxic tumor regression through restoration of p53 wild-type conformation and post-translational modifications.

Gogna R, Madan E, Kuppusamy P, Pati U. Gogna R, et al. Among authors: kuppusamy p. Cell Death Dis. 2012 Mar 15;3(3):e286. doi: 10.1038/cddis.2012.15. Cell Death Dis. 2012. PMID: 22419115 Free PMC article.

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