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Systematic drug sensitivity testing reveals synergistic growth inhibition by dasatinib or mTOR inhibitors with paclitaxel in ovarian granulosa cell tumor cells.
Haltia UM, Andersson N, Yadav B, Färkkilä A, Kulesskiy E, Kankainen M, Tang J, Bützow R, Riska A, Leminen A, Heikinheimo M, Kallioniemi O, Unkila-Kallio L, Wennerberg K, Aittokallio T, Anttonen M. Haltia UM, et al. Among authors: anttonen m. Gynecol Oncol. 2017 Mar;144(3):621-630. doi: 10.1016/j.ygyno.2016.12.016. Epub 2017 Jan 16. Gynecol Oncol. 2017. PMID: 28104295 Free article.
Serum vascular endothelial growth factor A (VEGF) is elevated in patients with ovarian granulosa cell tumor (GCT), and VEGF inhibition by bevacizumab induces apoptosis in GCT in vitro.
Färkkilä A, Pihlajoki M, Tauriala H, Bützow R, Leminen A, Unkila-Kallio L, Heikinheimo M, Anttonen M. Färkkilä A, et al. Among authors: anttonen m. J Clin Endocrinol Metab. 2011 Dec;96(12):E1973-81. doi: 10.1210/jc.2011-1812. Epub 2011 Oct 12. J Clin Endocrinol Metab. 2011. PMID: 21994955
GATA-4 regulates Bcl-2 expression in ovarian granulosa cell tumors.
Kyrönlahti A, Rämö M, Tamminen M, Unkila-Kallio L, Butzow R, Leminen A, Nemer M, Rahman N, Huhtaniemi I, Heikinheimo M, Anttonen M. Kyrönlahti A, et al. Among authors: anttonen m. Endocrinology. 2008 Nov;149(11):5635-42. doi: 10.1210/en.2008-0148. Epub 2008 Jul 24. Endocrinology. 2008. PMID: 18653721
GATA4 protects granulosa cell tumors from TRAIL-induced apoptosis.
Kyrönlahti A, Kauppinen M, Lind E, Unkila-Kallio L, Butzow R, Klefström J, Wilson DB, Anttonen M, Heikinheimo M. Kyrönlahti A, et al. Among authors: anttonen m. Endocr Relat Cancer. 2010 Jul 28;17(3):709-17. doi: 10.1677/ERC-10-0041. Print 2010 Sep. Endocr Relat Cancer. 2010. PMID: 20554787
47 results