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2,253 results

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Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regeneration.
Alvarez-Sola G, Uriarte I, Latasa MU, Fernandez-Barrena MG, Urtasun R, Elizalde M, Barcena-Varela M, Jiménez M, Chang HC, Barbero R, Catalán V, Rodríguez A, Frühbeck G, Gallego-Escuredo JM, Gavaldà-Navarro A, Villarroya F, Rodriguez-Ortigosa CM, Corrales FJ, Prieto J, Berraondo P, Berasain C, Avila MA. Alvarez-Sola G, et al. Among authors: chang hc. Gut. 2017 Oct;66(10):1818-1828. doi: 10.1136/gutjnl-2016-312975. Epub 2017 Jan 24. Gut. 2017. PMID: 28119353
Lack of Abcc3 expression impairs bile-acid induced liver growth and delays hepatic regeneration after partial hepatectomy in mice.
Fernández-Barrena MG, Monte MJ, Latasa MU, Uriarte I, Vicente E, Chang HC, Rodriguez-Ortigosa CM, Elferink RO, Berasain C, Marin JJ, Prieto J, Ávila MA. Fernández-Barrena MG, et al. Among authors: chang hc. J Hepatol. 2012 Feb;56(2):367-73. doi: 10.1016/j.jhep.2011.05.031. Epub 2011 Jul 12. J Hepatol. 2012. PMID: 21756856
Identification of fibroblast growth factor 15 as a novel mediator of liver regeneration and its application in the prevention of post-resection liver failure in mice.
Uriarte I, Fernandez-Barrena MG, Monte MJ, Latasa MU, Chang HC, Carotti S, Vespasiani-Gentilucci U, Morini S, Vicente E, Concepcion AR, Medina JF, Marin JJ, Berasain C, Prieto J, Avila MA. Uriarte I, et al. Among authors: chang hc. Gut. 2013 Jun;62(6):899-910. doi: 10.1136/gutjnl-2012-302945. Epub 2013 Jan 3. Gut. 2013. PMID: 23292666
X-box Binding Protein 1 Regulates Unfolded Protein, Acute-Phase, and DNA Damage Responses During Regeneration of Mouse Liver.
Argemí J, Kress TR, Chang HCY, Ferrero R, Bértolo C, Moreno H, González-Aparicio M, Uriarte I, Guembe L, Segura V, Hernández-Alcoceba R, Ávila MA, Amati B, Prieto J, Aragón T. Argemí J, et al. Gastroenterology. 2017 Apr;152(5):1203-1216.e15. doi: 10.1053/j.gastro.2016.12.040. Epub 2017 Jan 9. Gastroenterology. 2017. PMID: 28082079
Zolmitriptan: a novel portal hypotensive agent which synergizes with propranolol in lowering portal pressure.
Reboredo M, Chang HC, Barbero R, Rodríguez-Ortigosa CM, Pérez-Vizcaíno F, Morán A, García M, Banales JM, Carreño N, Alegre F, Herrero I, Quiroga J, Prieto J, Sangro B. Reboredo M, et al. Among authors: chang hc. PLoS One. 2013;8(1):e52683. doi: 10.1371/journal.pone.0052683. Epub 2013 Jan 16. PLoS One. 2013. PMID: 23341903 Free PMC article.
Discovery and safety profiling of a potent preclinical candidate, (4-[4-[[(3R)-3-(hydroxycarbamoyl)-8-azaspiro[4.5]decan-3-yl]sulfonyl]phenoxy]-N-methylbenzamide) (CM-352), for the prevention and treatment of hemorrhage.
Orbe J, Rodríguez JA, Sánchez-Arias JA, Salicio A, Belzunce M, Ugarte A, Chang HC, Rabal O, Oyarzabal J, Páramo JA. Orbe J, et al. Among authors: chang hc. J Med Chem. 2015 Apr 9;58(7):2941-57. doi: 10.1021/jm501939z. Epub 2015 Feb 25. J Med Chem. 2015. PMID: 25686022
2,253 results