Jerse AE - Search Results

1

Alanine 501 Mutations in Penicillin-Binding Protein 2 from Neisseria gonorrhoeae: Structure, Mechanism, and Effects on Cephalosporin Resistance and Biological Fitness.

Tomberg J, Fedarovich A, Vincent LR, Jerse AE, Unemo M, Davies C, Nicholas RA. Tomberg J, et al. Among authors: jerse ae. Biochemistry. 2017 Feb 28;56(8):1140-1150. doi: 10.1021/acs.biochem.6b01030. Epub 2017 Feb 16. Biochemistry. 2017. PMID: 28145684 Free PMC article.

2

Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC-MtrD-MtrE Efflux pump system confer different levels of antimicrobial resistance and in vivo fitness.

Warner DM, Shafer WM, Jerse AE. Warner DM, et al. Among authors: jerse ae. Mol Microbiol. 2008 Oct;70(2):462-78. doi: 10.1111/j.1365-2958.2008.06424.x. Epub 2008 Aug 27. Mol Microbiol. 2008. PMID: 18761689 Free PMC article.

3

A novel mechanism of high-level, broad-spectrum antibiotic resistance caused by a single base pair change in Neisseria gonorrhoeae.

Ohneck EA, Zalucki YM, Johnson PJ, Dhulipala V, Golparian D, Unemo M, Jerse AE, Shafer WM. Ohneck EA, et al. Among authors: jerse ae. mBio. 2011 Sep 20;2(5):e00187-11. doi: 10.1128/mBio.00187-11. Print 2011. mBio. 2011. PMID: 21933917 Free PMC article.

4

Impact of fluoroquinolone resistance mutations on gonococcal fitness and in vivo selection for compensatory mutations.

Kunz AN, Begum AA, Wu H, D'Ambrozio JA, Robinson JM, Shafer WM, Bash MC, Jerse AE. Kunz AN, et al. Among authors: jerse ae. J Infect Dis. 2012 Jun 15;205(12):1821-9. doi: 10.1093/infdis/jis277. Epub 2012 Apr 5. J Infect Dis. 2012. PMID: 22492860 Free PMC article.

5

Lipid A's structure mediates Neisseria gonorrhoeae fitness during experimental infection of mice and men.

Hobbs MM, Anderson JE, Balthazar JT, Kandler JL, Carlson RW, Ganguly J, Begum AA, Duncan JA, Lin JT, Sparling PF, Jerse AE, Shafer WM. Hobbs MM, et al. Among authors: jerse ae. mBio. 2013 Nov 19;4(6):e00892-13. doi: 10.1128/mBio.00892-13. mBio. 2013. PMID: 24255126 Free PMC article.

6

Phase-variable expression of lptA modulates the resistance of Neisseria gonorrhoeae to cationic antimicrobial peptides.

Kandler JL, Joseph SJ, Balthazar JT, Dhulipala V, Read TD, Jerse AE, Shafer WM. Kandler JL, et al. Among authors: jerse ae. Antimicrob Agents Chemother. 2014 Jul;58(7):4230-3. doi: 10.1128/AAC.03108-14. Epub 2014 May 12. Antimicrob Agents Chemother. 2014. PMID: 24820072 Free PMC article.

7

Proteomics-driven Antigen Discovery for Development of Vaccines Against Gonorrhea.

Zielke RA, Wierzbicki IH, Baarda BI, Gafken PR, Soge OO, Holmes KK, Jerse AE, Unemo M, Sikora AE. Zielke RA, et al. Among authors: jerse ae. Mol Cell Proteomics. 2016 Jul;15(7):2338-55. doi: 10.1074/mcp.M116.058800. Epub 2016 May 2. Mol Cell Proteomics. 2016. PMID: 27141096 Free PMC article.

8

Control of gdhR Expression in Neisseria gonorrhoeae via Autoregulation and a Master Repressor (MtrR) of a Drug Efflux Pump Operon.

Rouquette-Loughlin CE, Zalucki YM, Dhulipala VL, Balthazar JT, Doyle RG, Nicholas RA, Begum AA, Raterman EL, Jerse AE, Shafer WM. Rouquette-Loughlin CE, et al. Among authors: jerse ae. mBio. 2017 Apr 11;8(2):e00449-17. doi: 10.1128/mBio.00449-17. mBio. 2017. PMID: 28400529 Free PMC article.

9

In Vitro Susceptibility of Neisseria gonorrhoeae Strains to Mupirocin, an Antibiotic Reformulated for Parenteral Administration in Nanoliposomes.

Cern A, Connolly KL, Jerse AE, Barenholz Y. Cern A, et al. Among authors: jerse ae. Antimicrob Agents Chemother. 2018 Mar 27;62(4):e02377-17. doi: 10.1128/AAC.02377-17. Print 2018 Apr. Antimicrob Agents Chemother. 2018. PMID: 29339382 Free PMC article.

10

In Vivo-Selected Compensatory Mutations Restore the Fitness Cost of Mosaic penA Alleles That Confer Ceftriaxone Resistance in Neisseria gonorrhoeae.

Vincent LR, Kerr SR, Tan Y, Tomberg J, Raterman EL, Dunning Hotopp JC, Unemo M, Nicholas RA, Jerse AE. Vincent LR, et al. Among authors: jerse ae. mBio. 2018 Apr 3;9(2):e01905-17. doi: 10.1128/mBio.01905-17. mBio. 2018. PMID: 29615507 Free PMC article.

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