Unemo M - Search Results

1

Alanine 501 Mutations in Penicillin-Binding Protein 2 from Neisseria gonorrhoeae: Structure, Mechanism, and Effects on Cephalosporin Resistance and Biological Fitness.

Tomberg J, Fedarovich A, Vincent LR, Jerse AE, Unemo M, Davies C, Nicholas RA. Tomberg J, et al. Among authors: unemo m. Biochemistry. 2017 Feb 28;56(8):1140-1150. doi: 10.1021/acs.biochem.6b01030. Epub 2017 Feb 16. Biochemistry. 2017. PMID: 28145684 Free PMC article.

2

Neisseria gonorrhoeae isolates with reduced susceptibility to cefixime and ceftriaxone: association with genetic polymorphisms in penA, mtrR, porB1b, and ponA.

Lindberg R, Fredlund H, Nicholas R, Unemo M. Lindberg R, et al. Among authors: unemo m. Antimicrob Agents Chemother. 2007 Jun;51(6):2117-22. doi: 10.1128/AAC.01604-06. Epub 2007 Apr 9. Antimicrob Agents Chemother. 2007. PMID: 17420216 Free PMC article.

3

Genetics of chromosomally mediated intermediate resistance to ceftriaxone and cefixime in Neisseria gonorrhoeae.

Zhao S, Duncan M, Tomberg J, Davies C, Unemo M, Nicholas RA. Zhao S, et al. Among authors: unemo m. Antimicrob Agents Chemother. 2009 Sep;53(9):3744-51. doi: 10.1128/AAC.00304-09. Epub 2009 Jun 15. Antimicrob Agents Chemother. 2009. PMID: 19528266 Free PMC article.

4

Molecular and structural analysis of mosaic variants of penicillin-binding protein 2 conferring decreased susceptibility to expanded-spectrum cephalosporins in Neisseria gonorrhoeae: role of epistatic mutations.

Tomberg J, Unemo M, Davies C, Nicholas RA. Tomberg J, et al. Among authors: unemo m. Biochemistry. 2010 Sep 21;49(37):8062-70. doi: 10.1021/bi101167x. Biochemistry. 2010. PMID: 20704258 Free PMC article.

5

Emergence, spread and characteristics of Neisseria gonorrhoeae isolates with in vitro decreased susceptibility and resistance to extended-spectrum cephalosporins in Sweden.

Golparian D, Hellmark B, Fredlund H, Unemo M. Golparian D, et al. Among authors: unemo m. Sex Transm Infect. 2010 Nov;86(6):454-60. doi: 10.1136/sti.2010.045377. Sex Transm Infect. 2010. PMID: 20940159 Free article.

6

Cefpodoxime 10 μg disc screening test for detection of Neisseria gonorrhoeae with mosaic PBP2 and decreased susceptibility to extended-spectrum cephalosporins for public health purposes.

Limnios A, Tapsall J, Kahlmeter J, Hogan T, Ray S, Lam A, Unemo M. Limnios A, et al. Among authors: unemo m. APMIS. 2011 Jun;119(6):356-63. doi: 10.1111/j.1600-0463.2011.02729.x. Epub 2011 Feb 24. APMIS. 2011. PMID: 21569093

7

A novel mechanism of high-level, broad-spectrum antibiotic resistance caused by a single base pair change in Neisseria gonorrhoeae.

Ohneck EA, Zalucki YM, Johnson PJ, Dhulipala V, Golparian D, Unemo M, Jerse AE, Shafer WM. Ohneck EA, et al. Among authors: unemo m. mBio. 2011 Sep 20;2(5):e00187-11. doi: 10.1128/mBio.00187-11. Print 2011. mBio. 2011. PMID: 21933917 Free PMC article.

8

High-level cefixime- and ceftriaxone-resistant Neisseria gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure.

Unemo M, Golparian D, Nicholas R, Ohnishi M, Gallay A, Sednaoui P. Unemo M, et al. Antimicrob Agents Chemother. 2012 Mar;56(3):1273-80. doi: 10.1128/AAC.05760-11. Epub 2011 Dec 12. Antimicrob Agents Chemother. 2012. PMID: 22155830 Free PMC article.

9

In vitro activity of the new fluoroketolide solithromycin (CEM-101) against a large collection of clinical Neisseria gonorrhoeae isolates and international reference strains, including those with high-level antimicrobial resistance: potential treatment option for gonorrhea?

Golparian D, Fernandes P, Ohnishi M, Jensen JS, Unemo M. Golparian D, et al. Among authors: unemo m. Antimicrob Agents Chemother. 2012 May;56(5):2739-42. doi: 10.1128/AAC.00036-12. Epub 2012 Feb 21. Antimicrob Agents Chemother. 2012. PMID: 22354296 Free PMC article.

10

In vitro activity of ertapenem versus ceftriaxone against Neisseria gonorrhoeae isolates with highly diverse ceftriaxone MIC values and effects of ceftriaxone resistance determinants: ertapenem for treatment of gonorrhea?

Unemo M, Golparian D, Limnios A, Whiley D, Ohnishi M, Lahra MM, Tapsall JW. Unemo M, et al. Antimicrob Agents Chemother. 2012 Jul;56(7):3603-9. doi: 10.1128/AAC.00326-12. Epub 2012 Apr 30. Antimicrob Agents Chemother. 2012. PMID: 22547617 Free PMC article.

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