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Highly Potent, Selective, and Orally Bioavailable 4-Thiazol-N-(pyridin-2-yl)pyrimidin-2-amine Cyclin-Dependent Kinases 4 and 6 Inhibitors as Anticancer Drug Candidates: Design, Synthesis, and Evaluation.
Tadesse S, Yu M, Mekonnen LB, Lam F, Islam S, Tomusange K, Rahaman MH, Noll B, Basnet SK, Teo T, Albrecht H, Milne R, Wang S. Tadesse S, et al. J Med Chem. 2017 Mar 9;60(5):1892-1915. doi: 10.1021/acs.jmedchem.6b01670. Epub 2017 Feb 16. J Med Chem. 2017. PMID: 28156111 Free article.
CDK5 in oncology: recent advances and future prospects.
Lenjisa JL, Tadesse S, Khair NZ, Kumarasiri M, Yu M, Albrecht H, Milne R, Wang S. Lenjisa JL, et al. Among authors: tadesse s. Future Med Chem. 2017 Oct;9(16):1939-1962. doi: 10.4155/fmc-2017-0097. Epub 2017 Oct 27. Future Med Chem. 2017. PMID: 29076761 Review.
Discovery of CDK5 Inhibitors through Structure-Guided Approach.
Khair NZ, Lenjisa JL, Tadesse S, Kumarasiri M, Basnet SKC, Mekonnen LB, Li M, Diab S, Sykes MJ, Albrecht H, Milne R, Wang S. Khair NZ, et al. Among authors: tadesse s. ACS Med Chem Lett. 2019 Mar 20;10(5):786-791. doi: 10.1021/acsmedchemlett.9b00029. eCollection 2019 May 9. ACS Med Chem Lett. 2019. PMID: 31098000 Free PMC article.
Synthesis and structure-activity relationship study of pyrrolidine-oxadiazoles as anthelmintics against Haemonchus contortus.
Ruan B, Zhang Y, Tadesse S, Preston S, Taki AC, Jabbar A, Hofmann A, Jiao Y, Garcia-Bustos J, Harjani J, Le TG, Varghese S, Teguh S, Xie Y, Odiba J, Hu M, Gasser RB, Baell J. Ruan B, et al. Among authors: tadesse s. Eur J Med Chem. 2020 Mar 15;190:112100. doi: 10.1016/j.ejmech.2020.112100. Epub 2020 Jan 25. Eur J Med Chem. 2020. PMID: 32018095
214 results