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Highly Potent, Selective, and Orally Bioavailable 4-Thiazol-N-(pyridin-2-yl)pyrimidin-2-amine Cyclin-Dependent Kinases 4 and 6 Inhibitors as Anticancer Drug Candidates: Design, Synthesis, and Evaluation.
Tadesse S, Yu M, Mekonnen LB, Lam F, Islam S, Tomusange K, Rahaman MH, Noll B, Basnet SK, Teo T, Albrecht H, Milne R, Wang S. Tadesse S, et al. Among authors: teo t. J Med Chem. 2017 Mar 9;60(5):1892-1915. doi: 10.1021/acs.jmedchem.6b01670. Epub 2017 Feb 16. J Med Chem. 2017. PMID: 28156111 Free article.
Discovery of (E)-3-((styrylsulfonyl)methyl)pyridine and (E)-2-((styrylsulfonyl)methyl)pyridine derivatives as anticancer agents: synthesis, structure-activity relationships, and biological activities.
Lu T, Goh AW, Yu M, Adams J, Lam F, Teo T, Li P, Noll B, Zhong L, Diab S, Chahrour O, Hu A, Abbas AY, Liu X, Huang S, Sumby CJ, Milne R, Midgley C, Wang S. Lu T, et al. Among authors: teo t. J Med Chem. 2014 Mar 27;57(6):2275-91. doi: 10.1021/jm4019614. Epub 2014 Mar 10. J Med Chem. 2014. PMID: 24471873
MAP kinase-interacting kinases--emerging targets against cancer.
Diab S, Kumarasiri M, Yu M, Teo T, Proud C, Milne R, Wang S. Diab S, et al. Among authors: teo t. Chem Biol. 2014 Apr 24;21(4):441-452. doi: 10.1016/j.chembiol.2014.01.011. Epub 2014 Mar 6. Chem Biol. 2014. PMID: 24613018 Review.
Pharmacologic Inhibition of MNKs in Acute Myeloid Leukemia.
Teo T, Lam F, Yu M, Yang Y, Basnet SK, Albrecht H, Sykes MJ, Wang S. Teo T, et al. Mol Pharmacol. 2015 Aug;88(2):380-9. doi: 10.1124/mol.115.098012. Epub 2015 Jun 4. Mol Pharmacol. 2015. PMID: 26044548
269 results