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Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48.
Riazuddin S, Belyantseva IA, Giese AP, Lee K, Indzhykulian AA, Nandamuri SP, Yousaf R, Sinha GP, Lee S, Terrell D, Hegde RS, Ali RA, Anwar S, Andrade-Elizondo PB, Sirmaci A, Parise LV, Basit S, Wali A, Ayub M, Ansar M, Ahmad W, Khan SN, Akram J, Tekin M, Riazuddin S, Cook T, Buschbeck EK, Frolenkov GI, Leal SM, Friedman TB, Ahmed ZM. Riazuddin S, et al. Among authors: indzhykulian aa. Nat Genet. 2012 Nov;44(11):1265-71. doi: 10.1038/ng.2426. Epub 2012 Sep 30. Nat Genet. 2012. PMID: 23023331 Free PMC article.
Mini-PCDH15 gene therapy rescues hearing in a mouse model of Usher syndrome type 1F.
Ivanchenko MV, Hathaway DM, Klein AJ, Pan B, Strelkova O, De-la-Torre P, Wu X, Peters CW, Mulhall EM, Booth KT, Goldstein C, Brower J, Sotomayor M, Indzhykulian AA, Corey DP. Ivanchenko MV, et al. Among authors: indzhykulian aa. Nat Commun. 2023 Apr 26;14(1):2400. doi: 10.1038/s41467-023-38038-y. Nat Commun. 2023. PMID: 37100771 Free PMC article.
Primary cilia are not calcium-responsive mechanosensors.
Delling M, Indzhykulian AA, Liu X, Li Y, Xie T, Corey DP, Clapham DE. Delling M, et al. Among authors: indzhykulian aa. Nature. 2016 Mar 31;531(7596):656-60. doi: 10.1038/nature17426. Epub 2016 Mar 23. Nature. 2016. PMID: 27007841 Free PMC article.
Rescue of Hearing by Gene Delivery to Inner-Ear Hair Cells Using Exosome-Associated AAV.
György B, Sage C, Indzhykulian AA, Scheffer DI, Brisson AR, Tan S, Wu X, Volak A, Mu D, Tamvakologos PI, Li Y, Fitzpatrick Z, Ericsson M, Breakefield XO, Corey DP, Maguire CA. György B, et al. Among authors: indzhykulian aa. Mol Ther. 2017 Feb 1;25(2):379-391. doi: 10.1016/j.ymthe.2016.12.010. Epub 2017 Jan 9. Mol Ther. 2017. PMID: 28082074 Free PMC article.
Gene Transfer with AAV9-PHP.B Rescues Hearing in a Mouse Model of Usher Syndrome 3A and Transduces Hair Cells in a Non-human Primate.
György B, Meijer EJ, Ivanchenko MV, Tenneson K, Emond F, Hanlon KS, Indzhykulian AA, Volak A, Karavitaki KD, Tamvakologos PI, Vezina M, Berezovskii VK, Born RT, O'Brien M, Lafond JF, Arsenijevic Y, Kenna MA, Maguire CA, Corey DP. György B, et al. Among authors: indzhykulian aa. Mol Ther Methods Clin Dev. 2018 Nov 20;13:1-13. doi: 10.1016/j.omtm.2018.11.003. eCollection 2019 Jun 14. Mol Ther Methods Clin Dev. 2018. PMID: 30581889 Free PMC article.
Renewed proliferation in adult mouse cochlea and regeneration of hair cells.
Shu Y, Li W, Huang M, Quan YZ, Scheffer D, Tian C, Tao Y, Liu X, Hochedlinger K, Indzhykulian AA, Wang Z, Li H, Chen ZY. Shu Y, et al. Among authors: indzhykulian aa. Nat Commun. 2019 Dec 4;10(1):5530. doi: 10.1038/s41467-019-13157-7. Nat Commun. 2019. PMID: 31797926 Free PMC article.
Norrie disease protein is essential for cochlear hair cell maturation.
Hayashi Y, Chiang H, Tian C, Indzhykulian AA, Edge ASB. Hayashi Y, et al. Among authors: indzhykulian aa. Proc Natl Acad Sci U S A. 2021 Sep 28;118(39):e2106369118. doi: 10.1073/pnas.2106369118. Proc Natl Acad Sci U S A. 2021. PMID: 34544869 Free PMC article.
35 results