Pan B - Search Results

1

Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c.

Pan B, Askew C, Galvin A, Heman-Ackah S, Asai Y, Indzhykulian AA, Jodelka FM, Hastings ML, Lentz JJ, Vandenberghe LH, Holt JR, Géléoc GS. Pan B, et al. Nat Biotechnol. 2017 Mar;35(3):264-272. doi: 10.1038/nbt.3801. Epub 2017 Feb 6. Nat Biotechnol. 2017. PMID: 28165476 Free PMC article.

2

TMC1 and TMC2 are components of the mechanotransduction channel in hair cells of the mammalian inner ear.

Pan B, Géléoc GS, Asai Y, Horwitz GC, Kurima K, Ishikawa K, Kawashima Y, Griffith AJ, Holt JR. Pan B, et al. Neuron. 2013 Aug 7;79(3):504-15. doi: 10.1016/j.neuron.2013.06.019. Epub 2013 Jul 18. Neuron. 2013. PMID: 23871232 Free PMC article.

3

Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice.

Zou J, Zheng T, Ren C, Askew C, Liu XP, Pan B, Holt JR, Wang Y, Yang J. Zou J, et al. Among authors: pan b. Hum Mol Genet. 2014 May 1;23(9):2374-90. doi: 10.1093/hmg/ddt629. Epub 2013 Dec 11. Hum Mol Genet. 2014. PMID: 24334608 Free PMC article.

4

TMC function in hair cell transduction.

Holt JR, Pan B, Koussa MA, Asai Y. Holt JR, et al. Among authors: pan b. Hear Res. 2014 May;311:17-24. doi: 10.1016/j.heares.2014.01.001. Epub 2014 Jan 11. Hear Res. 2014. PMID: 24423408 Free PMC article. Review.

5

Transmembrane channel-like (TMC) genes are required for auditory and vestibular mechanosensation.

Kawashima Y, Kurima K, Pan B, Griffith AJ, Holt JR. Kawashima Y, et al. Among authors: pan b. Pflugers Arch. 2015 Jan;467(1):85-94. doi: 10.1007/s00424-014-1582-3. Epub 2014 Jul 31. Pflugers Arch. 2015. PMID: 25074487 Free PMC article. Review.

6

Tmc gene therapy restores auditory function in deaf mice.

Askew C, Rochat C, Pan B, Asai Y, Ahmed H, Child E, Schneider BL, Aebischer P, Holt JR. Askew C, et al. Among authors: pan b. Sci Transl Med. 2015 Jul 8;7(295):295ra108. doi: 10.1126/scitranslmed.aab1996. Sci Transl Med. 2015. PMID: 26157030 Free PMC article.

7

The molecules that mediate sensory transduction in the mammalian inner ear.

Pan B, Holt JR. Pan B, et al. Curr Opin Neurobiol. 2015 Oct;34:165-71. doi: 10.1016/j.conb.2015.06.013. Epub 2015 Jul 25. Curr Opin Neurobiol. 2015. PMID: 26218316 Free PMC article. Review.

8

TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell Stereocilia.

Kurima K, Ebrahim S, Pan B, Sedlacek M, Sengupta P, Millis BA, Cui R, Nakanishi H, Fujikawa T, Kawashima Y, Choi BY, Monahan K, Holt JR, Griffith AJ, Kachar B. Kurima K, et al. Among authors: pan b. Cell Rep. 2015 Sep 8;12(10):1606-17. doi: 10.1016/j.celrep.2015.07.058. Epub 2015 Aug 28. Cell Rep. 2015. PMID: 26321635 Free PMC article.

9

RNA Interference Prevents Autosomal-Dominant Hearing Loss.

Shibata SB, Ranum PT, Moteki H, Pan B, Goodwin AT, Goodman SS, Abbas PJ, Holt JR, Smith RJH. Shibata SB, et al. Among authors: pan b. Am J Hum Genet. 2016 Jun 2;98(6):1101-1113. doi: 10.1016/j.ajhg.2016.03.028. Epub 2016 May 26. Am J Hum Genet. 2016. PMID: 27236922 Free PMC article.

10

A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear.

Landegger LD, Pan B, Askew C, Wassmer SJ, Gluck SD, Galvin A, Taylor R, Forge A, Stankovic KM, Holt JR, Vandenberghe LH. Landegger LD, et al. Among authors: pan b. Nat Biotechnol. 2017 Mar;35(3):280-284. doi: 10.1038/nbt.3781. Epub 2017 Feb 6. Nat Biotechnol. 2017. PMID: 28165475 Free PMC article.

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