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Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects.
Busch R, Hobbs BD, Zhou J, Castaldi PJ, McGeachie MJ, Hardin ME, Hawrylkiewicz I, Sliwinski P, Yim JJ, Kim WJ, Kim DK, Agusti A, Make BJ, Crapo JD, Calverley PM, Donner CF, Lomas DA, Wouters EF, Vestbo J, Tal-Singer R, Bakke P, Gulsvik A, Litonjua AA, Sparrow D, Paré PD, Levy RD, Rennard SI, Beaty TH, Hokanson J, Silverman EK, Cho MH; National Emphysema Treatment Trial Genetics; Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-Points; International COPD Genetics Network; COPDGene Investigators. Busch R, et al. Among authors: lomas da. Am J Respir Cell Mol Biol. 2017 Jul;57(1):35-46. doi: 10.1165/rcmb.2016-0331OC. Am J Respir Cell Mol Biol. 2017. PMID: 28170284 Free PMC article.
Reduction of Z alpha-1 antitrypsin polymers in human iPSC-hepatocytes and mice by LRRK2 inhibitors.
Kent D, Ng SS, Syanda AM, Khoshkenar P, Ronzoni R, Li CZ, Zieger M, Greer C, Hatch S, Segal J, Blackford SJI, Im YR, Chowdary V, Ismaili T, Danovi D, Lewis PA, Irving JA, Sahdeo S, Lomas DA, Ebner D, Mueller C, Rashid ST. Kent D, et al. Among authors: lomas da. Hepatology. 2024 Jul 2. doi: 10.1097/HEP.0000000000000969. Online ahead of print. Hepatology. 2024. PMID: 38954820
The under-appreciated world of the serpin family of serine proteinase inhibitors.
Bouton MC, Geiger M, Sheffield WP, Irving JA, Lomas DA, Song S, Satyanarayanan RS, Zhang L, McFadden G, Lucas AR. Bouton MC, et al. Among authors: lomas da. EMBO Mol Med. 2023 Jun 7;15(6):e17144. doi: 10.15252/emmm.202217144. Epub 2023 May 9. EMBO Mol Med. 2023. PMID: 37158379 Free PMC article.
Keratin 8 is a scaffolding and regulatory protein of ERAD complexes.
Pranke IM, Chevalier B, Premchandar A, Baatallah N, Tomaszewski KF, Bitam S, Tondelier D, Golec A, Stolk J, Lukacs GL, Hiemstra PS, Dadlez M, Lomas DA, Irving JA, Delaunay-Moisan A, van Anken E, Hinzpeter A, Sermet-Gaudelus I, Edelman A. Pranke IM, et al. Among authors: lomas da. Cell Mol Life Sci. 2022 Sep;79(9):503. doi: 10.1007/s00018-022-04528-3. Epub 2022 Sep 1. Cell Mol Life Sci. 2022. PMID: 36045259
352 results