Hansen H - Search Results

1

An Endogenous TNF-α Antagonist Induced by Splice-switching Oligonucleotides Reduces Inflammation in Hepatitis and Arthritis Mouse Models.

Graziewicz MA, Tarrant TK, Buckley B, Roberts J, Fulton L, Hansen H, Ørum H, Kole R, Sazani P. Graziewicz MA, et al. Among authors: hansen h. Mol Ther. 2008 Jul;16(7):1316-1322. doi: 10.1038/mt.2008.85. Epub 2016 Dec 8. Mol Ther. 2008. PMID: 28178484

2

An endogenous TNF-alpha antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models.

Graziewicz MA, Tarrant TK, Buckley B, Roberts J, Fulton L, Hansen H, Ørum H, Kole R, Sazani P. Graziewicz MA, et al. Among authors: hansen h. Mol Ther. 2008 Jul;16(7):1316-22. doi: 10.1038/mt.2008.85. Epub 2008 May 6. Mol Ther. 2008. PMID: 18461057 Free PMC article.

3

PCSK9 LNA antisense oligonucleotides induce sustained reduction of LDL cholesterol in nonhuman primates.

Lindholm MW, Elmén J, Fisker N, Hansen HF, Persson R, Møller MR, Rosenbohm C, Ørum H, Straarup EM, Koch T. Lindholm MW, et al. Among authors: hansen hf. Mol Ther. 2012 Feb;20(2):376-81. doi: 10.1038/mt.2011.260. Epub 2011 Nov 22. Mol Ther. 2012. PMID: 22108858 Free PMC article.

4

Short locked nucleic acid antisense oligonucleotides potently reduce apolipoprotein B mRNA and serum cholesterol in mice and non-human primates.

Straarup EM, Fisker N, Hedtjärn M, Lindholm MW, Rosenbohm C, Aarup V, Hansen HF, Ørum H, Hansen JB, Koch T. Straarup EM, et al. Among authors: hansen jb, hansen hf. Nucleic Acids Res. 2010 Nov;38(20):7100-11. doi: 10.1093/nar/gkq457. Epub 2010 Jul 8. Nucleic Acids Res. 2010. PMID: 20615897 Free PMC article.

5

Expanding the design horizon of antisense oligonucleotides with alpha-L-LNA.

Frieden M, Christensen SM, Mikkelsen ND, Rosenbohm C, Thrue CA, Westergaard M, Hansen HF, Ørum H, Koch T. Frieden M, et al. Among authors: hansen hf. Nucleic Acids Res. 2003 Nov 1;31(21):6365-72. doi: 10.1093/nar/gkg820. Nucleic Acids Res. 2003. PMID: 14576324 Free PMC article.

6

Electronic Structures of LNA Phosphorothioate Oligonucleotides.

Bohr HG, Shim I, Stein C, Ørum H, Hansen HF, Koch T. Bohr HG, et al. Among authors: hansen hf. Mol Ther Nucleic Acids. 2017 Sep 15;8:428-441. doi: 10.1016/j.omtn.2017.05.011. Epub 2017 Jun 1. Mol Ther Nucleic Acids. 2017. PMID: 28918042 Free PMC article.

7

A locked nucleic acid oligonucleotide targeting microRNA 122 is well-tolerated in cynomolgus monkeys.

Hildebrandt-Eriksen ES, Aarup V, Persson R, Hansen HF, Munk ME, Ørum H. Hildebrandt-Eriksen ES, et al. Among authors: hansen hf. Nucleic Acid Ther. 2012 Jun;22(3):152-61. doi: 10.1089/nat.2011.0332. Epub 2012 Apr 30. Nucleic Acid Ther. 2012. PMID: 22545703

8

SPC3042: a proapoptotic survivin inhibitor.

Hansen JB, Fisker N, Westergaard M, Kjaerulff LS, Hansen HF, Thrue CA, Rosenbohm C, Wissenbach M, Orum H, Koch T. Hansen JB, et al. Among authors: hansen hf. Mol Cancer Ther. 2008 Sep;7(9):2736-45. doi: 10.1158/1535-7163.MCT-08-0161. Mol Cancer Ther. 2008. PMID: 18790754 Free article.

9

Improvements in automated PNA synthesis using Boc/Z monomers.

Koch T, Hansen HF, Andersen P, Larsen T, Batz HG, Otteson K, Orum H. Koch T, et al. Among authors: hansen hf. J Pept Res. 1997 Jan;49(1):80-8. doi: 10.1111/j.1399-3011.1997.tb01124.x. J Pept Res. 1997. PMID: 9128104

10

PNA synthesis using a novel Boc/acyl protecting group strategy.

Kofoed T, Hansen HF, Orum H, Koch T. Kofoed T, et al. Among authors: hansen hf. J Pept Sci. 2001 Aug;7(8):402-12. doi: 10.1002/psc.333. J Pept Sci. 2001. PMID: 11548056

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