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Senescent cells expose and secrete an oxidized form of membrane-bound vimentin as revealed by a natural polyreactive antibody.
Frescas D, Roux CM, Aygun-Sunar S, Gleiberman AS, Krasnov P, Kurnasov OV, Strom E, Virtuoso LP, Wrobel M, Osterman AL, Antoch MP, Mett V, Chernova OB, Gudkov AV. Frescas D, et al. Among authors: krasnov p. Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):E1668-E1677. doi: 10.1073/pnas.1614661114. Epub 2017 Feb 13. Proc Natl Acad Sci U S A. 2017. PMID: 28193858 Free PMC article.
Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells.
Hall BM, Balan V, Gleiberman AS, Strom E, Krasnov P, Virtuoso LP, Rydkina E, Vujcic S, Balan K, Gitlin I, Leonova K, Polinsky A, Chernova OB, Gudkov AV. Hall BM, et al. Among authors: krasnov p. Aging (Albany NY). 2016 Jul;8(7):1294-315. doi: 10.18632/aging.100991. Aging (Albany NY). 2016. PMID: 27391570 Free PMC article.
Immune checkpoint protein VSIG4 as a biomarker of aging in murine adipose tissue.
Hall BM, Gleiberman AS, Strom E, Krasnov PA, Frescas D, Vujcic S, Leontieva OV, Antoch MP, Kogan V, Koman IE, Zhu Y, Tchkonia T, Kirkland JL, Chernova OB, Gudkov AV. Hall BM, et al. Among authors: krasnov pa. Aging Cell. 2020 Oct;19(10):e13219. doi: 10.1111/acel.13219. Epub 2020 Aug 28. Aging Cell. 2020. PMID: 32856419 Free PMC article.
p16(Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli.
Hall BM, Balan V, Gleiberman AS, Strom E, Krasnov P, Virtuoso LP, Rydkina E, Vujcic S, Balan K, Gitlin II, Leonova KI, Consiglio CR, Gollnick SO, Chernova OB, Gudkov AV. Hall BM, et al. Among authors: krasnov p. Aging (Albany NY). 2017 Aug 2;9(8):1867-1884. doi: 10.18632/aging.101268. Aging (Albany NY). 2017. PMID: 28768895 Free PMC article.
Genetic approaches identify adult pituitary stem cells.
Gleiberman AS, Michurina T, Encinas JM, Roig JL, Krasnov P, Balordi F, Fishell G, Rosenfeld MG, Enikolopov G. Gleiberman AS, et al. Among authors: krasnov p. Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6332-7. doi: 10.1073/pnas.0801644105. Epub 2008 Apr 24. Proc Natl Acad Sci U S A. 2008. PMID: 18436641 Free PMC article.
OT-82, a novel anticancer drug candidate that targets the strong dependence of hematological malignancies on NAD biosynthesis.
Korotchkina L, Kazyulkin D, Komarov PG, Polinsky A, Andrianova EL, Joshi S, Gupta M, Vujcic S, Kononov E, Toshkov I, Tian Y, Krasnov P, Chernov MV, Veith J, Antoch MP, Middlemiss S, Somers K, Lock RB, Norris MD, Henderson MJ, Haber M, Chernova OB, Gudkov AV. Korotchkina L, et al. Among authors: krasnov p. Leukemia. 2020 Jul;34(7):1828-1839. doi: 10.1038/s41375-019-0692-5. Epub 2020 Jan 2. Leukemia. 2020. PMID: 31896781 Free PMC article.
The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates.
Krivokrysenko VI, Toshkov IA, Gleiberman AS, Krasnov P, Shyshynova I, Bespalov I, Maitra RK, Narizhneva NV, Singh VK, Whitnall MH, Purmal AA, Shakhov AN, Gudkov AV, Feinstein E. Krivokrysenko VI, et al. Among authors: krasnov p. PLoS One. 2015 Sep 14;10(9):e0135388. doi: 10.1371/journal.pone.0135388. eCollection 2015. PLoS One. 2015. PMID: 26367124 Free PMC article.
Prevention and mitigation of acute radiation syndrome in mice by synthetic lipopeptide agonists of Toll-like receptor 2 (TLR2).
Shakhov AN, Singh VK, Bone F, Cheney A, Kononov Y, Krasnov P, Bratanova-Toshkova TK, Shakhova VV, Young J, Weil MM, Panoskaltsis-Mortari A, Orschell CM, Baker PS, Gudkov A, Feinstein E. Shakhov AN, et al. Among authors: krasnov p. PLoS One. 2012;7(3):e33044. doi: 10.1371/journal.pone.0033044. Epub 2012 Mar 27. PLoS One. 2012. PMID: 22479357 Free PMC article.
36 results