Galea GL - Search Results

1

Neural tube closure: cellular, molecular and biomechanical mechanisms.

Nikolopoulou E, Galea GL, Rolo A, Greene ND, Copp AJ. Nikolopoulou E, et al. Among authors: galea gl. Development. 2017 Feb 15;144(4):552-566. doi: 10.1242/dev.145904. Development. 2017. PMID: 28196803 Free PMC article. Review.

2

Planar cell polarity aligns osteoblast division in response to substrate strain.

Galea GL, Meakin LB, Savery D, Taipaleenmaki H, Delisser P, Stein GS, Copp AJ, van Wijnen AJ, Lanyon LE, Price JS. Galea GL, et al. J Bone Miner Res. 2015 Mar;30(3):423-35. doi: 10.1002/jbmr.2377. J Bone Miner Res. 2015. PMID: 25264362 Free PMC article.

3

Biomechanical coupling facilitates spinal neural tube closure in mouse embryos.

Galea GL, Cho YJ, Galea G, Molè MA, Rolo A, Savery D, Moulding D, Culshaw LH, Nikolopoulou E, Greene NDE, Copp AJ. Galea GL, et al. Among authors: galea g. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5177-E5186. doi: 10.1073/pnas.1700934114. Epub 2017 Jun 12. Proc Natl Acad Sci U S A. 2017. PMID: 28607062 Free PMC article.

4

Valproic acid disrupts the biomechanics of late spinal neural tube closure in mouse embryos.

Hughes A, Greene NDE, Copp AJ, Galea GL. Hughes A, et al. Among authors: galea gl. Mech Dev. 2018 Feb;149:20-26. doi: 10.1016/j.mod.2017.12.001. Epub 2017 Dec 7. Mech Dev. 2018. PMID: 29225143 Free PMC article.

5

Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice.

Orriss IR, Lanham S, Savery D, Greene NDE, Stanier P, Oreffo R, Copp AJ, Galea GL. Orriss IR, et al. Among authors: galea gl. Sci Rep. 2018 Feb 20;8(1):3325. doi: 10.1038/s41598-018-21718-x. Sci Rep. 2018. PMID: 29463853 Free PMC article.

6

Vangl2 disruption alters the biomechanics of late spinal neurulation leading to spina bifida in mouse embryos.

Galea GL, Nychyk O, Mole MA, Moulding D, Savery D, Nikolopoulou E, Henderson DJ, Greene NDE, Copp AJ. Galea GL, et al. Dis Model Mech. 2018 Mar 21;11(3):dmm032219. doi: 10.1242/dmm.032219. Dis Model Mech. 2018. PMID: 29590636 Free PMC article.

7

Overexpression of Grainyhead-like 3 causes spina bifida and interacts genetically with mutant alleles of Grhl2 and Vangl2 in mice.

De Castro SCP, Gustavsson P, Marshall AR, Gordon WM, Galea G, Nikolopoulou E, Savery D, Rolo A, Stanier P, Andersen B, Copp AJ, Greene NDE. De Castro SCP, et al. Hum Mol Genet. 2018 Dec 15;27(24):4218-4230. doi: 10.1093/hmg/ddy313. Hum Mol Genet. 2018. PMID: 30189017 Free PMC article.

8

Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2.

Nikolopoulou E, Hirst CS, Galea G, Venturini C, Moulding D, Marshall AR, Rolo A, De Castro SCP, Copp AJ, Greene NDE. Nikolopoulou E, et al. Nat Commun. 2019 Jun 6;10(1):2487. doi: 10.1038/s41467-019-10164-6. Nat Commun. 2019. PMID: 31171776 Free PMC article.

9

Rho kinase-dependent apical constriction counteracts M-phase apical expansion to enable mouse neural tube closure.

Butler MB, Short NE, Maniou E, Alexandre P, Greene NDE, Copp AJ, Galea GL. Butler MB, et al. Among authors: galea gl. J Cell Sci. 2019 Jul 1;132(13):jcs230300. doi: 10.1242/jcs.230300. J Cell Sci. 2019. PMID: 31182644 Free PMC article.

10

Novel mouse model of encephalocele: post-neurulation origin and relationship to open neural tube defects.

Rolo A, Galea GL, Savery D, Greene NDE, Copp AJ. Rolo A, et al. Among authors: galea gl. Dis Model Mech. 2019 Nov 14;12(11):dmm040683. doi: 10.1242/dmm.040683. Dis Model Mech. 2019. PMID: 31628096 Free PMC article.

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