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An engineered transforming growth factor β (TGF-β) monomer that functions as a dominant negative to block TGF-β signaling.
Kim SK, Barron L, Hinck CS, Petrunak EM, Cano KE, Thangirala A, Iskra B, Brothers M, Vonberg M, Leal B, Richter B, Kodali R, Taylor AB, Du S, Barnes CO, Sulea T, Calero G, Hart PJ, Hart MJ, Demeler B, Hinck AP. Kim SK, et al. Among authors: barnes co. J Biol Chem. 2017 Apr 28;292(17):7173-7188. doi: 10.1074/jbc.M116.768754. Epub 2017 Feb 22. J Biol Chem. 2017. PMID: 28228478 Free PMC article.
MicroED Structure of Au146(p-MBA)57 at Subatomic Resolution Reveals a Twinned FCC Cluster.
Vergara S, Lukes DA, Martynowycz MW, Santiago U, Plascencia-Villa G, Weiss SC, de la Cruz MJ, Black DM, Alvarez MM, López-Lozano X, Barnes CO, Lin G, Weissker HC, Whetten RL, Gonen T, Yacaman MJ, Calero G. Vergara S, et al. Among authors: barnes co. J Phys Chem Lett. 2017 Nov 16;8(22):5523-5530. doi: 10.1021/acs.jpclett.7b02621. Epub 2017 Oct 31. J Phys Chem Lett. 2017. PMID: 29072840 Free PMC article.
Use of transmission electron microscopy to identify nanocrystals of challenging protein targets.
Stevenson HP, Makhov AM, Calero M, Edwards AL, Zeldin OB, Mathews II, Lin G, Barnes CO, Santamaria H, Ross TM, Soltis SM, Khosla C, Nagarajan V, Conway JF, Cohen AE, Calero G. Stevenson HP, et al. Among authors: barnes co. Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8470-5. doi: 10.1073/pnas.1400240111. Epub 2014 May 28. Proc Natl Acad Sci U S A. 2014. PMID: 24872454 Free PMC article.
The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.
Barnes CO, Wu Y, Song J, Lin G, Baxter EL, Brewster AS, Nagarajan V, Holmes A, Soltis SM, Sauter NK, Ahn J, Cohen AE, Calero G. Barnes CO, et al. Proc Natl Acad Sci U S A. 2019 May 7;116(19):9333-9339. doi: 10.1073/pnas.1814999116. Epub 2019 Apr 24. Proc Natl Acad Sci U S A. 2019. PMID: 31019074 Free PMC article.
Structural basis of transcription: RNA Polymerase II substrate binding and metal coordination at 3.0 Å using a free-electron laser.
Lin G, Barnes CO, Weiss S, Dutagaci B, Qiu C, Feig M, Song J, Lyubimov A, Cohen AE, Kaplan CD, Calero G. Lin G, et al. Among authors: barnes co. bioRxiv [Preprint]. 2023 Sep 22:2023.09.22.559052. doi: 10.1101/2023.09.22.559052. bioRxiv. 2023. Update in: Proc Natl Acad Sci U S A. 2024 Sep 3;121(36):e2318527121. doi: 10.1073/pnas.2318527121 PMID: 37790421 Free PMC article. Updated. Preprint.
Goniometer-based femtosecond crystallography with X-ray free electron lasers.
Cohen AE, Soltis SM, González A, Aguila L, Alonso-Mori R, Barnes CO, Baxter EL, Brehmer W, Brewster AS, Brunger AT, Calero G, Chang JF, Chollet M, Ehrensberger P, Eriksson TL, Feng Y, Hattne J, Hedman B, Hollenbeck M, Holton JM, Keable S, Kobilka BK, Kovaleva EG, Kruse AC, Lemke HT, Lin G, Lyubimov AY, Manglik A, Mathews II, McPhillips SE, Nelson S, Peters JW, Sauter NK, Smith CA, Song J, Stevenson HP, Tsai Y, Uervirojnangkoorn M, Vinetsky V, Wakatsuki S, Weis WI, Zadvornyy OA, Zeldin OB, Zhu D, Hodgson KO. Cohen AE, et al. Among authors: barnes co. Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17122-7. doi: 10.1073/pnas.1418733111. Epub 2014 Oct 31. Proc Natl Acad Sci U S A. 2014. PMID: 25362050 Free PMC article.
68 results