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An engineered transforming growth factor β (TGF-β) monomer that functions as a dominant negative to block TGF-β signaling.
Kim SK, Barron L, Hinck CS, Petrunak EM, Cano KE, Thangirala A, Iskra B, Brothers M, Vonberg M, Leal B, Richter B, Kodali R, Taylor AB, Du S, Barnes CO, Sulea T, Calero G, Hart PJ, Hart MJ, Demeler B, Hinck AP. Kim SK, et al. Among authors: barron l. J Biol Chem. 2017 Apr 28;292(17):7173-7188. doi: 10.1074/jbc.M116.768754. Epub 2017 Feb 22. J Biol Chem. 2017. PMID: 28228478 Free PMC article.
Binding Properties of the Transforming Growth Factor-β Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling.
Villarreal MM, Kim SK, Barron L, Kodali R, Baardsnes J, Hinck CS, Krzysiak TC, Henen MA, Pakhomova O, Mendoza V, O'Connor-McCourt MD, Lafer EM, López-Casillas F, Hinck AP. Villarreal MM, et al. Among authors: barron l. Biochemistry. 2016 Dec 13;55(49):6880-6896. doi: 10.1021/acs.biochem.6b00566. Epub 2016 Dec 2. Biochemistry. 2016. PMID: 27951653 Free PMC article.
A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands.
Qin T, Barron L, Xia L, Huang H, Villarreal MM, Zwaagstra J, Collins C, Yang J, Zwieb C, Kodali R, Hinck CS, Kim SK, Reddick RL, Shu C, O'Connor-McCourt MD, Hinck AP, Sun LZ. Qin T, et al. Among authors: barron l. Oncotarget. 2016 Dec 27;7(52):86087-86102. doi: 10.18632/oncotarget.13343. Oncotarget. 2016. PMID: 27863384 Free PMC article.
Correction to Binding Properties of the Transforming Growth Factor-β Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling.
Villarreal MM, Kim SK, Barron L, Kodali R, Baardsnes J, Hinck CS, Krzysiak TC, Henen MA, Pakhomova O, Mendoza V, O'Connor-McCourt MD, Lafer EM, López-Casillas F, Hinck AP. Villarreal MM, et al. Among authors: barron l. Biochemistry. 2017 Jul 18;56(28):3689. doi: 10.1021/acs.biochem.7b00566. Epub 2017 Jul 5. Biochemistry. 2017. PMID: 28677957 Free PMC article. No abstract available.
Correction: A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands.
Qin T, Barron L, Xia L, Huang H, Villarreal MM, Zwaagstra J, Collins C, Yang J, Zwieb C, Kodali R, Hinck CS, Kim SK, Reddick RL, Shu C, O'Connor-McCourt MD, Hinck AP, Sun LZ. Qin T, et al. Among authors: barron l. Oncotarget. 2017 Aug 21;8(34):57905. doi: 10.18632/oncotarget.20370. eCollection 2017 Aug 22. Oncotarget. 2017. PMID: 28915722 Free PMC article.
449 results