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An engineered transforming growth factor β (TGF-β) monomer that functions as a dominant negative to block TGF-β signaling.
Kim SK, Barron L, Hinck CS, Petrunak EM, Cano KE, Thangirala A, Iskra B, Brothers M, Vonberg M, Leal B, Richter B, Kodali R, Taylor AB, Du S, Barnes CO, Sulea T, Calero G, Hart PJ, Hart MJ, Demeler B, Hinck AP. Kim SK, et al. Among authors: kodali r. J Biol Chem. 2017 Apr 28;292(17):7173-7188. doi: 10.1074/jbc.M116.768754. Epub 2017 Feb 22. J Biol Chem. 2017. PMID: 28228478 Free PMC article.
A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands.
Qin T, Barron L, Xia L, Huang H, Villarreal MM, Zwaagstra J, Collins C, Yang J, Zwieb C, Kodali R, Hinck CS, Kim SK, Reddick RL, Shu C, O'Connor-McCourt MD, Hinck AP, Sun LZ. Qin T, et al. Among authors: kodali r. Oncotarget. 2016 Dec 27;7(52):86087-86102. doi: 10.18632/oncotarget.13343. Oncotarget. 2016. PMID: 27863384 Free PMC article.
A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells.
Johnston CJC, Smyth DJ, Kodali RB, White MPJ, Harcus Y, Filbey KJ, Hewitson JP, Hinck CS, Ivens A, Kemter AM, Kildemoes AO, Le Bihan T, Soares DC, Anderton SM, Brenn T, Wigmore SJ, Woodcock HV, Chambers RC, Hinck AP, McSorley HJ, Maizels RM. Johnston CJC, et al. Nat Commun. 2017 Nov 23;8(1):1741. doi: 10.1038/s41467-017-01886-6. Nat Commun. 2017. PMID: 29170498 Free PMC article.
Correction: A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands.
Qin T, Barron L, Xia L, Huang H, Villarreal MM, Zwaagstra J, Collins C, Yang J, Zwieb C, Kodali R, Hinck CS, Kim SK, Reddick RL, Shu C, O'Connor-McCourt MD, Hinck AP, Sun LZ. Qin T, et al. Among authors: kodali r. Oncotarget. 2017 Aug 21;8(34):57905. doi: 10.18632/oncotarget.20370. eCollection 2017 Aug 22. Oncotarget. 2017. PMID: 28915722 Free PMC article.
RAD52 is required for RNA-templated recombination repair in post-mitotic neurons.
Welty S, Teng Y, Liang Z, Zhao W, Sanders LH, Greenamyre JT, Rubio ME, Thathiah A, Kodali R, Wetzel R, Levine AS, Lan L. Welty S, et al. Among authors: kodali r. J Biol Chem. 2018 Jan 26;293(4):1353-1362. doi: 10.1074/jbc.M117.808402. Epub 2017 Dec 7. J Biol Chem. 2018. PMID: 29217771 Free PMC article.
93 results