O'Donnell V - Search Results

1

Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo.

Lauder SN, Tyrrell VJ, Allen-Redpath K, Aldrovandi M, Gray D, Collins P, Jones SA, Taylor PR, O'Donnell V. Lauder SN, et al. Wellcome Open Res. 2017 Jan 4;2:1. doi: 10.12688/wellcomeopenres.10308.1. Wellcome Open Res. 2017. PMID: 28239665 Free PMC article.

2

Characterization of nitric oxide consumption pathways by normal, chronic granulomatous disease and myeloperoxidase-deficient human neutrophils.

Clark SR, Coffey MJ, Maclean RM, Collins PW, Lewis MJ, Cross AR, O'Donnell VB. Clark SR, et al. J Immunol. 2002 Nov 15;169(10):5889-96. doi: 10.4049/jimmunol.169.10.5889. J Immunol. 2002. PMID: 12421972

3

Classic interleukin-6 receptor signaling and interleukin-6 trans-signaling differentially control angiotensin II-dependent hypertension, cardiac signal transducer and activator of transcription-3 activation, and vascular hypertrophy in vivo.

Coles B, Fielding CA, Rose-John S, Scheller J, Jones SA, O'Donnell VB. Coles B, et al. Am J Pathol. 2007 Jul;171(1):315-25. doi: 10.2353/ajpath.2007.061078. Am J Pathol. 2007. PMID: 17591976 Free PMC article.

4

Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFNgamma-dependent iNOS expression in the vasculature of healthy mice.

Morton J, Coles B, Wright K, Gallimore A, Morrow JD, Terry ES, Anning PB, Morgan BP, Dioszeghy V, Kühn H, Chaitidis P, Hobbs AJ, Jones SA, O'Donnell VB. Morton J, et al. Blood. 2008 May 15;111(10):5187-94. doi: 10.1182/blood-2007-10-117283. Epub 2008 Feb 15. Blood. 2008. PMID: 18281503 Free PMC article.

5

12/15-Lipoxygenase regulates the inflammatory response to bacterial products in vivo.

Dioszeghy V, Rosas M, Maskrey BH, Colmont C, Topley N, Chaitidis P, Kühn H, Jones SA, Taylor PR, O'Donnell VB. Dioszeghy V, et al. J Immunol. 2008 Nov 1;181(9):6514-24. doi: 10.4049/jimmunol.181.9.6514. J Immunol. 2008. PMID: 18941242

6

Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease.

Morgan AH, Dioszeghy V, Maskrey BH, Thomas CP, Clark SR, Mathie SA, Lloyd CM, Kühn H, Topley N, Coles BC, Taylor PR, Jones SA, O'Donnell VB. Morgan AH, et al. J Biol Chem. 2009 Aug 7;284(32):21185-91. doi: 10.1074/jbc.M109.021634. Epub 2009 Jun 15. J Biol Chem. 2009. PMID: 19531470 Free PMC article.

7

Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation.

Thomas CP, Morgan LT, Maskrey BH, Murphy RC, Kühn H, Hazen SL, Goodall AH, Hamali HA, Collins PW, O'Donnell VB. Thomas CP, et al. J Biol Chem. 2010 Mar 5;285(10):6891-903. doi: 10.1074/jbc.M109.078428. Epub 2010 Jan 8. J Biol Chem. 2010. PMID: 20061396 Free PMC article.

8

Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection.

Clark SR, Guy CJ, Scurr MJ, Taylor PR, Kift-Morgan AP, Hammond VJ, Thomas CP, Coles B, Roberts GW, Eberl M, Jones SA, Topley N, Kotecha S, O'Donnell VB. Clark SR, et al. Blood. 2011 Feb 10;117(6):2033-43. doi: 10.1182/blood-2010-04-278887. Epub 2010 Dec 21. Blood. 2011. PMID: 21177434 Free PMC article.

9

Paracetamol reduces influenza-induced immunopathology in a mouse model of infection without compromising virus clearance or the generation of protective immunity.

Lauder SN, Taylor PR, Clark SR, Evans RL, Hindley JP, Smart K, Leach H, Kidd EJ, Broadley KJ, Jones SA, Wise MP, Godkin AJ, O'Donnell V, Gallimore AM. Lauder SN, et al. Thorax. 2011 May;66(5):368-74. doi: 10.1136/thx.2010.150318. Epub 2011 Feb 10. Thorax. 2011. PMID: 21310755 Free PMC article.

10

Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ.

Hammond VJ, Morgan AH, Lauder S, Thomas CP, Brown S, Freeman BA, Lloyd CM, Davies J, Bush A, Levonen AL, Kansanen E, Villacorta L, Chen YE, Porter N, Garcia-Diaz YM, Schopfer FJ, O'Donnell VB. Hammond VJ, et al. J Biol Chem. 2012 Dec 7;287(50):41651-66. doi: 10.1074/jbc.M112.405407. Epub 2012 Oct 11. J Biol Chem. 2012. PMID: 23060450 Free PMC article. Clinical Trial.

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